Effect of intermittent administration of neurokinin 3 receptor agonist on luteinizing hormone secretion, estrus, and ovulation in feed-restricted goats

Endo, Natsumi; Tanaka, Tomomi

doi:10.1016/j.smallrumres.2015.04.011

Cited by 3 publications

(1 citation statement)

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“…This suggests that stimulation of LH release by senktide can enhance the development and production of E 2 from the follicles, and this increased E 2 concentration further induces estrus and endogenous LH surge for subsequent ovulation in some cases. Due to the limitations of clinical trials, further studies were performed to determine the effect of senktide on LH secretion, follicular development, estrus, and ovulation in feed-restricted goats [ 63 ]. Feed restriction was applied to mimic the nutritional status of anestrus patients.…”

Section: Strategies For the Treatment Of Estrus And Ovulation Disordersmentioning

confidence: 99%

Possible causes and treatment strategies for the estrus and ovulation disorders in dairy cows

Endo

2022

Journal of Reproduction and Development

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The reproductive performance of dairy cows has declined, along with an increase in their milk yield. First-service conception rates in lactating dairy cows are often lower than 50%. The precise detection of estrus is an important factor in the reproductive management of dairy cows for successful fertilization and pregnancy. However, estrus expression has been decreasing in modern dairy cows, affecting the detection rate of estrus. In addition to estrus, a high incidence of ovulation disorders affects the fertility of dairy cows. To address these problems, it is necessary to understand the changes in the endocrine functions that underlie estrus and ovulation disorders, and to develop effective treatment strategies. Recent studies have revealed that neurokinin B and neurokinin 3 receptor signaling play important roles in the regulation of the secretion of gonadotropin-releasing and luteinizing hormones, suggesting a potential clinical avenue for the stimulation of gonadal function. In this review, I have discussed the problems in estrus and ovulation disorders in modern dairy cows as well as the possible applications of neurokinin 3 receptor agonists in the treatment of these disorders.

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Section: Strategies For the Treatment Of Estrus And Ovulation Disordersmentioning

confidence: 99%

Possible causes and treatment strategies for the estrus and ovulation disorders in dairy cows

Endo

2022

Journal of Reproduction and Development

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Smartphone-based rapid quantitative detection of luteinizing hormone using gold immunochromatographic strip

Liu

Fan

Kong

et al. 2018

Sensors and Actuators B: Chemical

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A rapid quantitative determination method of Luteinizing hormone with gold immunochromatographic strip

Liu

Kong

Yang

et al. 2017

2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Measurement of Luteinizing hormone (LH) levels is of great importance in guidance for pregnancy, diagnosis of ovarian diseases and evaluation of clinical effect. Gold immunochromatographic strip(GICS) assay is a rapid, simple, low-costs, and on-site technology. Quantitative detection of GICS has advantage over the traditional qualitative or semi-quantitative strip assay. In this paper, we developed a novel quantitative detection method for GICS based on smart-phone. First, smart-phone was used to acquire GICS image. Then, we applied the canny edge detection operator to extract the reading window from GICS image, and the fuzzy c-means (FCM) clustering algorithm to locate the test and control lines in the reading window. In order to reduce environmental interference, luminance compensation based on color constancy algorithms was applied. Finally, the property of the developed quantitative method is demonstrated by the detection of LH sample and clinical serum sample. Experimental results revealed that this method could achieve a low detection limit of 1.0 mIU/mL in a linear range from 1.0 to 125.0 mIU/mL. Furthermore, the proposed method could be used for the determination of clinical serum samples and its corresponding correlation coefficients were 0.964. Results showed that this novel method could be an effective tool for the rapid quantitative determination of LH.

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Effect of intermittent administration of neurokinin 3 receptor agonist on luteinizing hormone secretion, estrus, and ovulation in feed-restricted goats

Cited by 3 publications

References 32 publications

Possible causes and treatment strategies for the estrus and ovulation disorders in dairy cows

Possible causes and treatment strategies for the estrus and ovulation disorders in dairy cows

Smartphone-based rapid quantitative detection of luteinizing hormone using gold immunochromatographic strip

A rapid quantitative determination method of Luteinizing hormone with gold immunochromatographic strip

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