Effect of intense pulsed light using acne filter on eyelid margin telangiectasia in moderate-to-severe meibomian gland dysfunction

Han, Jung Yeob; Lee, Yunhan; Nam, Sanghyu; Moon, Su Young; Lee, Hun; Kim, Jae Yong; Tchah, Hungwon

doi:10.1007/s10103-021-03482-z

Cited by 10 publications

(23 citation statements)

References 48 publications

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“…However, to the best of our knowledge, there are no studies on IPL treatment using a vascular filter in the ophthalmology field, and this study is the first to report the evaluation of the effect of IPL treatment using a vascular filter in MGD patients. As in the previous study on acne filter utility [30], IPL treatment using the novel dual-band filter emitting 530-650 nm and 900-1200 nm is effective to treat MGD patients.…”

Section: Discussionsupporting

confidence: 52%

“…However, all these studies used the existing 590 nm filter, and studies reporting the use of the novel dual-band filters in the treatment of IPL in MGD patients are rare. In the ophthalmology fields, only one study reported IPL treatment using an acne filter in MGD patients [30]. However, to the best of our knowledge, there are no studies on IPL treatment using a vascular filter in the ophthalmology field, and this study is the first to report the evaluation of the effect of IPL treatment using a vascular filter in MGD patients.…”

Section: Discussionmentioning

confidence: 82%

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Effect of Intense Pulsed-Light Treatment Using a Novel Dual-Band Filter in Patients with Meibomian Gland Dysfunction

Kim

Min

2022

JCM

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Background: This study evaluates the effect of intense pulsed-light (IPL) treatment in patients with meibomian gland dysfunction (MGD) using a novel dual-band filter (vascular filter, 530–650 nm and 900–1200 nm) and compares it with the effect and discomfort during treatment using a conventional filter. Methods: The medical records of 89 patients (89 eyes) with MGD who underwent IPL treatment were reviewed. Patients treated with the vascular filter or conventional 590 nm filter were designated as Group A or Group B, respectively. Patients underwent IPL treatment four times every four weeks. Ocular surface disease index (OSDI) scores, dry eye (DE), and MGD parameters were determined before the first IPL treatment and after the fourth IPL treatment. Visual analog scale (VAS) scores were obtained at every IPL treatment. OSDI, DE and MGD parameters, and VAS were compared between the groups. Results: OSDI, DE, and MGD parameters improved after the four IPL treatments in both groups. There were no significant differences, between the groups, in OSDI, DE, and MGD parameters, before the first IPL treatment and after the fourth IPL treatment. VAS at each of the IPL treatments was lower in Group B than in Group A. Conclusion: IPL treatment using the novel vascular filter for patients with MGD is effective compared with conventional IPL treatment for MGD patients.

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Section: Discussionsupporting

confidence: 52%

Section: Discussionmentioning

confidence: 82%

Effect of Intense Pulsed-Light Treatment Using a Novel Dual-Band Filter in Patients with Meibomian Gland Dysfunction

Kim

Min

2022

JCM

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“…The 600–800 nm wavelength light is mainly absorbed by melanin, inducing pain. On the contrary, the hemoglobin in the superficial and deep tissue vasculatures absorbs light of 400–600 nm and 800–1200 nm, respectively [ 20 ]. The energy from the IPL device can be focused on a vascular structure, especially the lid margin telangiectasia, and destroy the abnormal vascular lesion around the lid margin.…”

Section: Introductionmentioning

confidence: 99%

“…The energy from the IPL device can be focused on a vascular structure, especially the lid margin telangiectasia, and destroy the abnormal vascular lesion around the lid margin. There was a significant improvement in the lid margin telangiectasia of both the upper and lower eyelids four weeks after IPL treatment using an acne filter; subjective symptoms and clinical signs improved, as well [ 20 ]. Similar to the acne filter, the vascular filter is a notched filter that can emit light of shorter wavelengths (530–650 nm) to target the porphyrins and hemoglobin in superficial blood vessels, and light of longer wavelengths (900–1200 nm) to target the hemoglobin in deep blood vessels.…”

Section: Introductionmentioning

confidence: 99%

Investigation of Prognostic Factors for Intense Pulsed Light Treatment with a Vascular Filter in Patients with Moderate or Severe Meibomian Gland Dysfunction

Lee

Jang

Nam

et al. 2022

JCM

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We aimed to investigate the prognostic factors for, and treatment efficacy of, intense pulsed light (IPL) treatment with a vascular filter in patients with moderate or severe meibomian gland dysfunction (MGD). In this retrospective observational study, 58 moderate or severe MGD patients who underwent IPL treatment with a vascular filter were enrolled. IPL treatment was administered to the upper and lower eyelids four times at two-week intervals. At baseline, and four weeks after IPL, we evaluated the matrix metalloproteinase (MMP)-9 expression levels, tear break-up times (TBUT), ocular surface staining scores, lid margin telangiectasias, and meibomian gland characteristics. The subjective symptoms and adverse effects were reviewed and recorded. Regression analyses were performed to explore the prognostic factors affecting clinical outcomes. IPL treatment using a vascular filter led to improvements in the TBUT, ocular surface staining score, meibomian gland grade, meibum quality and consistency, lid margin telangiectasia, and symptom score (all p < 0.001). Furthermore, the positivity rate (90.2% to 70.6%, p = 0.013) and expression levels (1.92 ± 1.18 to 1.24 ± 1.18, p < 0.001) of tear MMP-9 improved after the IPL treatment. In multivariate logistic regression analysis, a young age (odds ratio = 0.867, p = 0.007) and a toothpaste-like consistency in the upper lid (odds ratio = 8.449, p = 0.046) were associated with improvements in the meibomian gland grade. No adverse effects were detected. IPL with a vascular filter is a safe and effective treatment for moderate and severe MGD. Age and the meibum consistency in the upper lid are important prognostic factors.

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“…Существуют различия в графике применения данных устройств. Так, система E > Eye обычно используется в виде трех или четырех сеансов, проводимых в 1, 15, 45 и 75 дни, в то время как применение системы M22 ограничивается двумя сеансами с промежутком в 3-4 недели [37][38][39].…”

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Modern Possibilities of Physiotherapeutic Treatment in Meibomian Gland Dysfunction

et al. 2022

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Currently, the main applied physiotherapeutic methods of treatment, whale, as well as the features of their application are considered. The basis of the meibomian glands dysfunction treatment is the hygiene of the eyelids. There are many modifications to the application of eyelid hygiene, but its basic principle is the use of warm compresses and eyelid massage. There are many modifications of warm compresses. Using them, it is necessary to remember about the possibility of the appearance of the cornea with various types of thermal effects on the eyelids when dysfunction of the meibomian glands is detected, therefore it is important to carefully dose the time of thermal exposure and temperature regime, which allows you to avoid side effects. The classic tool that a doctor uses to treat MGD — eyelid massage on a glass rod, has now been replaced by many high-tech devices for heating, moisturizing and massage of the eyelid. All commercial devices for the treatment of MGD on the world market can be divided into several groups, according to their effect: device for light therapy. The most high-tech devices include the LipiFlow® device (combined heat and eyelid massage) and the device for IPL therapy with intense pulsed light. many studies aimed at studying the effectiveness of various research methods. It should be noted that it is not by chance that in modern ophthalmological practice the range of new methods for studying MGD has expanded so much. This is due to the annual number of patients suffering from this pathology. Therefore, the urgent task is to search for new methods of treatment aimed at restoring the functional activity of the meibomian glands.

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Effect of intense pulsed light using acne filter on eyelid margin telangiectasia in moderate-to-severe meibomian gland dysfunction

Cited by 10 publications

References 48 publications

Effect of Intense Pulsed-Light Treatment Using a Novel Dual-Band Filter in Patients with Meibomian Gland Dysfunction

Effect of Intense Pulsed-Light Treatment Using a Novel Dual-Band Filter in Patients with Meibomian Gland Dysfunction

Investigation of Prognostic Factors for Intense Pulsed Light Treatment with a Vascular Filter in Patients with Moderate or Severe Meibomian Gland Dysfunction

Modern Possibilities of Physiotherapeutic Treatment in Meibomian Gland Dysfunction

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