Effect of injection of β-carotene or vitamin E and selenium on fertility of lactating dairy cows

Aréchiga, C. F.; Vázquez-Flores, Sonia; Ortiz, Oskar; Hernández-Cerón, Joel; Porras, A.; McDowell, L. R.; Hansen, P. J.

doi:10.1016/s0093-691x(98)00114-9

Cited by 75 publications

(54 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, the results of different field trials have been inconsistent. Supplementation with vitamin E and Se 21 days before expected calving increased pregnancy rates (Arechiga et al., ), but when supplemented 30 days after calving, it did not improve first service conception rate (Arechiga et al., ). In the study by Campbell and Miller (), supplementing cows with vitamin E at a 1000 IU/day rate during the last 42 days pre‐partum reduced the interval from calving to first oestrus.…”

Section: Benefits Of Antioxidant Supplementationmentioning

confidence: 99%

The importance of the oxidative status of dairy cattle in the periparturient period: revisiting antioxidant supplementation

Abuelo

Hernández

Benedito

et al. 2014

Animal Physiology Nutrition

191

157

View full text Add to dashboard Cite

SummaryDairy cows are especially vulnerable to health disorders during the transition period, when they shift from late pregnancy to the onset of lactation. Diseases at this stage affect not only the animals' well-being, but also cause a major economic impact in dairy farms, because apart from treatment costs, affected cows will not reach their peak milk-producing capacity. The overproduction of reactive oxygen species (ROS) leads to oxidative stress, which has been identified as an underlying factor of dysfunctional inflammatory responses. Supplementation with vitamins and trace elements attempts to minimize the harmful consequences of excessive ROS production, thereby trying to improve animals' health status and to reduce disease incidence. However, results regarding the effects of supplementing antioxidants on dairy cows' health and performance have been inconsistent, because in most cases, the antioxidant potential of the animals was not assessed beforehand and the nutritional strategy planned accordingly. Therefore, reviewing the physiological and harmful effects of ROS production, along with the different options available for assessing the redox balance in dairy cattle and some of the key findings of different supplementation trials, could bring one step forward the on-farm application of determinations of oxidative status for establishing nutritional strategies early enough in the dry period that could improve transition cow health.

show abstract

Section: Benefits Of Antioxidant Supplementationmentioning

confidence: 99%

The importance of the oxidative status of dairy cattle in the periparturient period: revisiting antioxidant supplementation

Abuelo

Hernández

Benedito

et al. 2014

Animal Physiology Nutrition

191

157

View full text Add to dashboard Cite

show abstract

“…Arechiga et al [51] tested three intramuscular injections of 800 mg BC at Days-6 and -3 before and at the time of insemination with synchronized estrus. The concentrations of plasma BC (before the first injection, 270 ± 38 µg/dl; 24 h after the first injection, 555 ± 38 µg/dl) and those of ROLE (retinyl palmitate: before the first injection, 40 ± 7 µg/dl; 24 h after the first injection, 108 ± 7 µg/dl) were increased after the first injection and remained at elevated levels until the end of the blood sampling period (13 days after the last injection).…”

Section: Effects Of Vitamin a In Artificial Insemination (Ai) In Cattlementioning

confidence: 99%

The Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

Ikeda

Kitagawa

Imai

et al. 2005

Journal of Reproduction and Development

View full text Add to dashboard Cite

Abstract. Vitamin A is one of the micronutrients which have been implicated in cattle reproduction.In cattle, ingested vitamin A, mainly as β-carotene (BC) from forages and retinol ester from formula feed, is metabolized and transported to the oocytes and cumulus-granulosa cells in ovarian follicles through binding to various interacting molecules. The active form of vitamin A, retinoic acid (RA), functions as a regulator of gene expression in these targets. Early research showed the positive effects of vitamin A supplementation on bovine fertility in artificial insemination, and several studies on effects of vitamin A metabolites used in other artificial reproductive techniques (ART), including superovulation, ovum pick up, and in vitro maturation culture have provided evidence for the specific roles of vitamin A in oocyte cytoplasmic maturation (acquisition of developmental competence of oocytes during their meiotic maturation period for the embryonic development after fertilization). BC may enhance cytoplasmic maturation by its antioxidant properties which cannot be replaced by RA. Furthermore, RA may promote cytoplasmic maturation of bovine oocytes via its modulatory effects on the gene expression of gonadotrophin receptors, midkine, cyclooxygenase-2, and nitric oxide synthase in cumulus-granulosa cells. Key words: Vitamin A, Cattle, Oocyte, Cytoplasmic maturation (J. Reprod. Dev. 51: [23][24][25][26][27][28][29][30][31][32][33][34][35] 2005) itamin A is one of the fat-soluble vitamins and is well known to regulate development, cellular growth and differentiation, and tissue function [1,2]. Since the earliest research into vitamin A function in cattle reproduction [3,4], vitamin A and its metabolites (Fig. 1) have been tested in various artificial reproduction techniques (ART) in cattle. It has been found so far that vitamin A and its metabolites affect ovarian follicular growth [5] and steroidogenesis [6], oviductal and uterine environments [7,8], immune functions [9-11], oocyte maturation, and embryo and conceptus development [12].Oocytes are formed during fetal life and are arrested at the prophase stage of the first meiotic division. After puberty, the fully grown oocyte arrested at the first meiotic prophase, the germinal vesicle stage, in the last folliclular wave [13] within the estrous cycle resumes meiosis in response to a preovulatory luteinizing hormone (LH) surge and reaches the metaphase stage of the second meiotic division. This process is called oocyte maturation [14] and is considered to involve not only the resumption of meiosis (nuclear maturation) but also the acquisition of developmental competence ( c y t o p l a s m i c m a t u r a t i o n ) f o r e m b r y o n i c d e v e l o p m e n t a f t e r f e r t i l i z a t i o n [ 1 5 , 1 6 ] .

show abstract

“…Selenium supplementation to diets has been reported to improve reproductive performance in mice, sheep and cattle (Sanders, 1984;Tang et al, 1991;Van Ryssen et al, 1992;Aréchiga et al, 1998), while others have not found association between herd milk and blood Se concentrations and fertility parameters (Ropstad and Refsdal, 1987;Jukola et al, 1996).…”

Section: Introductionmentioning

confidence: 99%

Immunocytochemical Localisation of Phospholipid Hydroperoxide Glutathione Peroxidase in Bull’s Spermatogenic Cells

Parillo

Sylla

Palombi

et al. 2014

Italian Journal of Animal Science

View full text Add to dashboard Cite

Phospholipid hydroperoxide glutathione peroxidase (PHGPx) is a selenoprotein, which protects biomembranes from oxidative damages, and it also accounts for almost the entire selenium content of mammalian testis. The present investigation was performed to localise PHGPx in the testis and in epididymal and ejaculated spermatozoa of the bull by using light and electron immunomicroscopy. The study also aimed to further clarify the possible functions of the protein in bull fertility. In the testis, spermatogenic cells of the adluminal tubular compartment showed cytoplasmatic immunostaining; whereas, in the epididymal and ejaculated spermatozoa immunostaining was specifically localised at the level of the head and mid-piece. Ultrastructural data revealed the presence of signals for PHGPx in different subcellular compartments of maturing and mature sperm (mitochondria, chromatin, nuclear envelope, acrosomes, cytoskeletal structures) suggesting that this enzyme plays versatile and important biological roles during spermatogenesis. The final localisation of the immunostaining at acrosomal level puts forward a new role of the protein which further emphasises its relevance in male reproduction: it is reported to anchor substrate of the sperm acrosome to the oocyte zona pellucida during the fertilisation process.

show abstract

Effect of injection of β-carotene or vitamin E and selenium on fertility of lactating dairy cows

Cited by 75 publications

References 39 publications

The importance of the oxidative status of dairy cattle in the periparturient period: revisiting antioxidant supplementation

The importance of the oxidative status of dairy cattle in the periparturient period: revisiting antioxidant supplementation

The Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

Immunocytochemical Localisation of Phospholipid Hydroperoxide Glutathione Peroxidase in Bull’s Spermatogenic Cells

Contact Info

Product

Resources

About