Effect of inhomogeneities and source position on dose distribution of nucletron high dose rate Ir-192 brachytherapy source by Monte Carlo simulation

Abstract

The results can be used in TPS.

Effect of tissue composition on dose distribution in brachytherapy with various photon emitting sources

“…The relative dose difference along the transverse axis of the source was 5.5-6.5% higher and 4.5-5% lower in the presence of air and cortical bone, respectively. The results were in good agreement with other data in the literature [15]. Cazeca et al .…”

Evaluation of brachytherapy lung implant dose distributions from photon‐emitting sources due to tissue heterogeneities

“…These agreed with literature results for 192 Ir. 15 Unlike some studies in which only a single source was involved and only several points at a certain distance were investigated, 16 the multiple sources and volume of interest approach in this study provided more clinicallyrelevant results for lung brachytherapy implants.…”

“…While lung tissue heterogeneities have been investigated, only high-energy sources such as 192 Ir and 137 Cs have been examined. [14][15][16] Therefore, research on accurate brachytherapy dose calculations for low-energy lung implants should be performed.…”

Monte Carlo study of dosimetric parameters and dose distribution effect of inhomogeneities and source position of GammaMed Plus source

“…[5] In this calculated study, the uncertainties of dose rate have been evaluated according to the recommendations of TG-43U1 considering the type A or statistical uncertainty due to the MC simulation of photon histories in dose rate and air kerma These results are found in good agreement with literature data. [8][9][10] Figure 7 illustrates the data and graph between strength simulation and the type B uncertainty due to the contribution of underlying cross section data and that arising from the source geometrical model. In the simulation in water, the uncertainty in dose rate along the transverse axis is approximately equal to 0.5 % except along the longitudinal axis where it has reached to more or less 1%.…”

“…Pantelis et al [7] show that if the source position near or far from the surface of patient is not taken into consideration, the central breast dose is overestimated of the order of 5%, and all other points of the breast is overestimated 10% in HDR brachytherapy of breast. Similarly, the effect of inhomogeneities like cortical bone and air, and source position on dose distribution is done by Chandola et al [8,9] and Terribilini et al [10] Apart from radiation−tissue interaction study, MC simulation is used to solve various physical problems. MC simulation calculations are based on random sampling techniques and are capable to collect the information based on large number of histories.…”