Effect of increasing levels of glycerin on growth rate, carcass traits and liver gluconeogenesis in young bulls

Ladeira, Márcio Machado; Carvalho, José Rodolfo Reis de; Chizzotti, Antônio; Teixeira, Priscilla Dutra; Dias, Júlio César Oliveira; Gionbelli, Tathyane Ramalho Santos; Rodrigues, A. C.; Oliveira, De

doi:10.1016/j.anifeedsci.2016.06.010

Cited by 12 publications

(8 citation statements)

References 27 publications

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“…These differences in TG profile may be partially explained by the different requirements of TG mobilization in order to release fatty acids so that they are oxidized in the mitochondrial matrix as a source of energy for animal growth, which may be supported by the impact of treatments on mitochondrial beta-oxidation of the longchain fatty acids pathway. Ladeira et al (2016Ladeira et al ( , 2018 reported that higher levels of glycerol in the muscle, as suggested in F-H animals in the present study, may be indicative of TG hydrolysis, which may support mitochondrial oxidation as lower levels of free carnitine may reflect utilization for long-chain fatty acid transport into the mitochondria. In the present work, F-H animals had higher hexadecanedioic acid mono-Lcarnitine ester and stearoylcarnitine concentration than P-L animals (Supporting Information Table S2), which aid in the mechanism whereby long-chain fatty acids are transferred from the cytosol to the mitochondrial matrix to undergo beta-oxidation.…”

Section: Discussionsupporting

confidence: 66%

“…Feedlot-fed animals are commonly subjected to a high-energy diet, which provides greater substrate availability that leads to increased propionate in the rumen and therefore glucose production, which is related to increased muscle and fat deposition (Ladeira et al, 2016;Wicks et al, 2019). In contrast, nutrient intakes are often below animal requirements for maximal growth in a pasture system, which affects animal growth and lean tissue and fat deposition (Mwangi et al, 2019;Wicks et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

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Variations in Intramuscular Fat Content and Profile in Angus × Nellore Steers Under Different Feeding Strategies Contribute to Color and Tenderness Development in Longissimus thoracis

Antonelo

Beline

Silva

et al. 2022

Meat and Muscle Biology

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Muscle from cattle reared under different finishing regime (grain vs. forage) and growth rate may have divergent metabolic signatures that are reflective of their inherent differences in biochemical processes that may impact its subsequent transformation into high quality beef. Differences in muscle lipid profiles were characterized in Angus x Nellore crossbred steers, using multiple reaction monitoring (MRM)-profiling, to identify potential metabolic signatures correlated to beef color and tenderness in the longissimus thoracis muscle of cattle fed in either a feedlot- or pasture-based system programmed to achieve either a high or low growth rate. A total of 440 MRMs were significant, which were related mainly to triglycerides and phosphatidylcholine lipids. Distinct clusters between feeding strategies for the lipid dataset were revealed, which affected glycerolipid metabolism (P = 0.004), phospholipid metabolism (P = 0.009), sphingolipid metabolism (P = 0.050) and mitochondrial beta-oxidation of long chain saturated fatty acids (P = 0.073) pathways. Lipid content and profile differed to feeding strategies, which were related to L*, a*, and tenderness. These findings provide a comprehensive and in-depth understanding of lipidomic profiling of beef cattle finished under different feeding strategies and provides a basis for the relationship between lipid content and profiles and beef quality development.

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Section: Discussionsupporting

confidence: 66%

Section: Introductionmentioning

confidence: 99%

Variations in Intramuscular Fat Content and Profile in Angus × Nellore Steers Under Different Feeding Strategies Contribute to Color and Tenderness Development in Longissimus thoracis

Antonelo

Beline

Silva

et al. 2022

Meat and Muscle Biology

View full text Add to dashboard Cite

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“…These results demonstrate a metabolic adjustment of the liver in response to increased plasma glycerol concentration and still indicate that there was no saturation of liver GK activity even when the dietary MCG concentration was 200 g/kg. Similarly, studies with broiler chickens (Bernardino et al 2014), fish and young bulls (Ladeira et al 2016) also showed a positive regulation of liver GK activity as a function of the increase of glycerin in the diet in order to allow a better utilization of the glycerol consumed by the animals.…”

Section: Discussionmentioning

confidence: 92%

Metabolism of glycerol in pigs fed diets containing mixed crude glycerin and β-adrenergic agonist

et al. 2019

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The optimised use of mixed crude glycerin (MCG) and ractopamine hydrochloride (RH) in diets for finishing pigs requires a better understanding of glycerol metabolism. Therefore, the present study evaluated the performance, blood parameters, metabolite concentrations in the Longissimus lumborum muscle and the activity of enzymes in the liver, subcutaneous adipose tissue and kidney of pigs fed diets containing MCG and/or RH. According to the initial weight, 64 barrows were distributed in a 4 × 2 factorial design, corresponding to four concentrations of MCG (0, 100, 150, and 200 g/kg) in diets containing 0 or 10 mg/kg of RH. There was no MCG × RH interaction for any of the evaluated parameters (P > 0.05). Moreover, there was no isolated effect of dietary MCG or RH on the weight gain and the blood concentrations of glucose, insulin, triacylglycerols, total cholesterol, total protein, albumin, creatinine, cortisol and lactate (P > 0.05). There was a higher rate of phosphorylation of glycerol in the liver, stimulation of lipogenesis in adipose tissue and a likely increase in the utilisation of glycerol by muscle fibres in response to an increased concentration of circulating glycerol from the diet (P < 0.05). In contrast, when the diet contained up to 200 g/kg MCG and 10 mg/kg RH, there were indications of a lower utilisation of glycerol for the synthesis of triacylglycerols in muscle, liver and adipose tissue, in addition to increased oxidation of amino acids in the liver followed by improved feed conversion of pigs (P < 0.05).

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“…Devido à riqueza em glicerol e gordura, a glicerina bruta vem sendo utilizada na alimentação animal como fonte de energia, substituindo o grão de milho nas rações (Silva et al, 2014;Lage et al, 2017). No metabolismo animal, o glicerol é convertido em glicose no fígado, via gliconeogênese, elevando o aporte energético para o animal (Ladeira et al, 2016). Em vacas, a oferta de glicerol incrementou a produção de insulina e, consequentemente, as taxas de concepção (León et al, 2010).…”

Section: Introductionunclassified

Análise espermática e testicular de touros Nelore suplementados com glicerina bruta

et al. 2019

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Objetivou-se avaliar os efeitos da inclusão de glicerina bruta sobre a morfologia testicular de touros Nelore. Para isso, foram utilizados 35 bovinos com peso corporal inicial de 428,0 ± 32,11 kg e aproximadamente 22 meses, distribuídos em delineamento inteiramente casualizado, com cinco tratamentos e sete repetições, suplementados durante 88 dias, com 14 dias de adaptação. Os tratamentos consistiram na inclusão de glicerina de baixa pureza nos níveis de 0, 3, 6, 9 e 12% da matéria seca total dos suplementos. Foi realizado uma coleta de sêmen no 88º dia experimental, posteriormente os animais foram pesados, abatidos e tiveram os testículos coletados, pesados e amostrados. A inclusão da glicerina bruta influenciou a motilidade e o vigor espermático (P<0,05). O peso corporal ao abate e perímetro escrotal não foram influenciados (P>0,05) pelos níveis de glicerina. Observou-se comportamento quadrático (P<0,05) para o índice Leydigossomático, com ponto de mínima de 6,66% e para a proporção volumétrica das células de Leydig (CL), com ponto de mínima de 5,41%. Não foram observadas alterações histopatológicas testiculares nos bovinos. A glicerina de baixa pureza promove modificações na motilidade e vigor espermático, no índice leydigossomático e no volume das células de Leydig. Portanto, não se recomenda a adição de glicerina bruta no suplemento de touros em atividade reprodutiva.

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Effect of increasing levels of glycerin on growth rate, carcass traits and liver gluconeogenesis in young bulls

Cited by 12 publications

References 27 publications

Variations in Intramuscular Fat Content and Profile in Angus × Nellore Steers Under Different Feeding Strategies Contribute to Color and Tenderness Development in Longissimus thoracis

Variations in Intramuscular Fat Content and Profile in Angus × Nellore Steers Under Different Feeding Strategies Contribute to Color and Tenderness Development in Longissimus thoracis

Metabolism of glycerol in pigs fed diets containing mixed crude glycerin and β-adrenergic agonist

Análise espermática e testicular de touros Nelore suplementados com glicerina bruta

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