Effect of increasing alkyl chain of 1st tier dendrimers on binding and release activities of methotrexate drug: An in vitro study

Hydration sphere structure of architectural molecules: Polyethylene glycol and polyoxymethylene oligomers

“…For example, polyethylene glycol (PEG) − a polymer made up of various units of ethylene glycol (CH2CH2O)n − is nontoxic, chemically inert, non-antigenic, highly soluble in water and in ethanol and has a high biocompatibility 5,6 . Along with these characteristics, PEG is FDA approved as an architectural molecule in for example drug carriers or multivalent inhibitors 7 . They can reduce the immunogenicity of biosimilar therapeutics and decrease renal clearance.…”