Effect of Impact on Chondrocyte Viability During Insertion of Human Osteochondral Grafts

Reengineering autologous bone grafts with the stem cell activator WNT3A

“…For example, even when freshly harvested BGM is maintained at room temperature there is significant cellular apoptosis [38,74,75]. In an effort to create a more effective biomaterial, we treated autografts with L-WNT3A and found that compared to control (untreated) BGM, BGM WNT exhibits~50% fewer TUNEL-positive cells [38].…”

Patellofemoral Osteochondral Allograft Transplantation

“…2). [18][19][20] Shell Technique Similar to the dowel technique, a size-, side-, and compartment-matched graft is obtained. The shell technique may at times be more technically challenging and therefore less frequently used than the dowel technique.…”

Articular cartilage surgery for the athlete

“…Borajani et al 62 studied cell viability from another perspective. They evaluated the effect of impact on the chondrocytes and confirmed that impact has a detrimental effect on cell viability; this has obvious implications for surgical technique.…”