Abstract:OBJECTIVE: To study the effect of K‐ras antisense oligodeoxynucleotides (ASODN) on human pancreatic cancer cell line PaTu 8988s at different times after treatment.
METHODS: Human pancreatic cancer cells (PaTu 8988s) in exponential growth stage were used at a cell concentration of 1 × 105/mL; 0.5 mL of the cell suspension was placed in each well of replicate 24‐well culture plates in the presence of different concentrations (50 and 100 μg/mL) of ASODN and sense oligodeoxynucleotides (SODN). Cell counts and 3‐[… Show more
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