Effect ofAPOEε4 and its modification by sociodemographic characteristics on cognitive measures in South Asians from LASI-DAD
Yi Zhe Wang,
Wei Zhao,
Priya Moorjani
et al.
Abstract:BACKGROUNDWe investigated effects ofAPOEε4 and its interactions with sociodemographic characteristics on cognitive measures in 2,563 South Asians from the Diagnostic Assessment of Dementia for the Longitudinal Aging Study of India (LASI-DAD).METHODSLinear regression models were used to assess the association betweenAPOEε4 and global- and domain-specific cognitive function. Effect modification by age, sex, and education were explored using cross-product interaction terms and subgroup analyses.RESULTSAPOEε4 was … Show more
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