Effect of hypothyrodism’s medication (T4) on implant osstointegration: A case series and literature search

Al-Hindi, Mariam; Alfotawi, Randa; Altamimi, Abdulaziz; Khalil, Osama; Alosaimi, Naif Ghazi Awadh Allah; AlGhamdi, Khalid M.; Heji, Khloud

doi:10.1016/j.ijscr.2021.01.040

Cited by 7 publications

(13 citation statements)

References 12 publications

(8 reference statements)

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“…Manual research of the reference list yielded no additional papers. As displayed in Table 1, the most recent article [14] was level 3 according to the SORT criteria [12], and the rest of the articles evaluated [15][16][17][18][19][20][21][22][23][24] were level 2. None of the articles were considered level 1.…”

Section: Resultsmentioning

confidence: 99%

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Patients with Thyroid Disorder, a Contraindication for Dental Implants? A Systematic Review

Torrejón-Moya

Izquierdo-Gómez

Pérez‐Sayáns

et al. 2022

JCM

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The thyroid gland is composed of the thyroid follicles, considered to be the functional units of the thyroid gland. The synthesis of the thyroid hormones occurs in these follicles. Triiodothyronine (T3) and thyroxine (T4) are the thyroid hormones and affect metabolic processes all through the body. This systematic evaluation was performed to answer the following PICO question: “Can patients with thyroid disorders undergo dental implant rehabilitation with the same survival rate as patients without thyroid disorders?”. A systematic review of the literature was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements to gather available and current evidence of thyroid disorders and its relationship with dental implants. The electronic search, in the PubMed and Cochrane databases, yielded 22 articles. Out of the 22 articles, only 11 fulfilled the inclusion criteria. Manual research of the reference list yielded no additional papers. According to the SORT criteria and answering our PICO question, level B can be established to conclude that patients with thyroid disorders can be rehabilitated with dental implants, with similar survival rates as patients without thyroid disorders. Papers with higher scientific evidence and bigger sample size should be carried out.

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Section: Resultsmentioning

confidence: 99%

“…None of the articles were considered level 1. From the 11 studies, 8 were cohort studies [15,16,[19][20][21][22][23][24], of which 6 were retrospective studies [15,16,19,20,22,23], 2 were prospective studies [21,24], and 2 were observational studies [17,18], which was a longitudinal study and 1 case series [14].…”

Section: Resultsmentioning

confidence: 99%

Patients with Thyroid Disorder, a Contraindication for Dental Implants? A Systematic Review

Torrejón-Moya

Izquierdo-Gómez

Pérez‐Sayáns

et al. 2022

JCM

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“…Abnormally decreased bone resorption in hypothyroidism is likely the reason that such patients experience less peri‐implant bone loss, even upon adjustment for potential confounders 156 . A demonstration study supported the successful placement and osseointegration of 17 dental implants up to 1 year follow‐up 157 …”

Section: Impact Of Systemic Driversmentioning

confidence: 88%

“…156 A demonstration study supported the successful placement and osseointegration of 17 dental implants up to 1 year follow-up. 157 In a study of 458 implants at a Spanish dental school, two medications were identified as protective against incident peri-implantitis, namely stomach acid reducing PPIs (OR = 0.08) and anticoagulants (OR = 0.08). 158 It should be mentioned that all major pharmaceutical groups have the potential to cause dry mouth, especially in polymedicated patients.…”

Section: Other Potentially Systemic Driversmentioning

confidence: 99%

Impact of local predisposing/precipitating factors and systemic drivers on peri‐implant diseases

Monje

Kan

Borgnakke

2022

Clin Implant Dent Rel Res

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Background Strong evidence suggests the infectious nature of peri‐implant diseases occurring in susceptible hosts. Epidemiological reports, though, indicate that peri‐implantitis is a site‐specific entity. Hence, the significance of local factors that may predispose/precipitate plaque accumulation and the impact of systemic drivers that alter the immune response are relevant in the prevention and management of peri‐implant disorders. Purpose The purpose of the present review is to shed light on the significance of local and systemic factors on peri‐implant diseases, making special emphasis on the associations with peri‐implantitis. Methods The biologic plausibility and supporting evidence aiming at providing a concluding remark were explored in the recent scientific literature for local predisposing/precipitating factors and systemic drivers related to peri‐implant diseases. Results Local predisposing factors such as soft tissue characteristics, implant position and prosthetic design proved being strongly associated with the occurrence of peri‐implant diseases. Hard tissue characteristics, however, failed to demonstrate having a direct association with peri‐implant diseases. Robust data points toward the strong link between residual sub‐mucosal cement and peri‐implant diseases, while limited data suggests the impact of residual sub‐mucosal floss and peri‐implantitis. Systemic drivers/habits such as hyperglycemia and smoking showed a strong negative impact on peri‐implantitis. However, there is insufficient evidence to claim for any link between metabolic syndrome, atherosclerotic cardiovascular disease, and obesity and peri‐implant diseases. Conclusion Local predisposing/precipitating factors and systemic drivers may increase the risk of peri‐implant diseases. Therefore, comprehensive anamnesis of the patients, educational/motivational programs and exhaustive prosthetically‐driven treatment planning must be fostered aiming at reducing the rate of biological complications in implant dentistry.

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“…Thyroxine hormones are T3 and T4, which are produced by the thyroid gland and control the metabolism of fats, carbohydrates, and proteins. Thyroxine is also necessary for healthy bone turnover and enhances the effects of other hormones, including growth hormone and catecholamines [49].…”

Section: Thyroid Disordersmentioning

confidence: 99%

Dental Implant Placement in Medically Compromised Patients: A Literature Review

Samara,

Moztarzadeh,

Hauer

et al. 2024

Cureus

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As a discipline of dentistry, oral implantology deals with the diagnosis, design, insertion, restoration, and/or management of alloplastic or autogenous oral structures for the purpose of regaining contour, function, aesthetics, and speech in a partially or completely edentulous patient. The present review aims to provide the currently available knowledge about the impact of certain systemic disorders and the usage of some medications on the survival rate of dental implant therapy and to highlight the importance of patient management under these conditions. Diabetes, osteoporosis, cardiovascular diseases, and the intake of some medications can increase the risk of the failure of a dental implant. Even though there are relatively few medical contraindications to dental implant treatment, certain conditions may increase the risk of failure or complications.

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Effect of hypothyrodism’s medication (T4) on implant osstointegration: A case series and literature search

Cited by 7 publications

References 12 publications

Patients with Thyroid Disorder, a Contraindication for Dental Implants? A Systematic Review

Patients with Thyroid Disorder, a Contraindication for Dental Implants? A Systematic Review

Impact of local predisposing/precipitating factors and systemic drivers on peri‐implant diseases

Dental Implant Placement in Medically Compromised Patients: A Literature Review

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