Effect of hypocaloric versus standard enteral feeding on clinical outcomes in critically ill adults – A meta-analysis of randomized controlled trials with trial sequential analysis

Zhou, Xiaoyang; Fang, Hanyuan; Hu, Caibao; Xu, Jun; Wang, H.; Pan, Junxiao; Sha, Yingying; Xu, Zhaojun

doi:10.1016/j.medine.2019.10.009

Cited by 1 publication

(1 citation statement)

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“…Conversely, the majority of RCTs did not confirm these observations. A recent systematic review by Zhou et al [22 ▪ ] observed no effect of hypocaloric feeding in the early phase of critical illness, with matched protein intake levels, on mortality and ICU or hospital length of stay. However, this systematic review included studies using predictive formulas and IC-derived measurements to calculate EE.…”

Section: Prevention Of Overfeeding In the Early Phasementioning

confidence: 99%

Current insights in ICU nutrition: tailored nutrition

Hermans

Laarhuis²,

Kouw

et al. 2023

Current Opinion in Critical Care

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Purpose of reviewTo summarize recent research on critical care nutrition focusing on the optimal composition, timing, and monitoring of enteral feeding strategies for (post)-ICU patients. We provide new insights on energy and protein recommendations, feeding intolerance, and describe nutritional practices for coronavirus disease 2019 ICU patients.Recent findingsThe use of indirect calorimetry to establish individual energy requirements for ICU patients is considered the gold standard. The limited research on optimal feeding targets in the early phase of critical illness suggests avoiding overfeeding. Protein provision based upon the absolute lean body mass is rational. Therefore, body composition measurements should be considered. Body impedance analysis and muscle ultrasound seem reliable, affordable, and accessible methods to assess body composition at the bedside. There is inadequate evidence to change our practice of continuous enteral feeding into intermittent feeding. Finally, severe acute respiratory syndrome coronavirus 2 patients are prone to underfeeding due to hypermetabolism and should be closely monitored.SummaryNutritional therapy should be adapted to the patient's characteristics, diagnosis, and state of metabolism during ICU stay and convalescence. A personalized nutrition plan may prevent harmful over- or underfeeding and attenuate muscle loss. Despite novel insights, more research is warranted into tailored nutrition strategies during critical illness and convalescence.

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Section: Prevention Of Overfeeding In the Early Phasementioning

confidence: 99%