Effect of hydroxyapatite coating on bony ingrowth into grooved titanium implants

Hayashi, K.; Mashima, T.; Uenoyama, K.; Hara, T.; Iwamoto, Y.

doi:10.1016/b978-008042692-1/50070-4

Cited by 8 publications

(9 citation statements)

References 2 publications

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“…The coat effect is limited to the immediate vicinity of the implants. Experimental and clinical nonresorbable plasma‐sprayed HA coats have shown bone‐HA contact 7, 38. Plasma‐ sprayed HA coatings have a strong and unquestionable osteoconductive effect, and have the ability of gap filling,39 but are also prone to delamination and degradation with subsequent increase in low‐grade inflammation by multinucleated giant cells and macrophages 9, 40.…”

Section: Discussionmentioning

confidence: 99%

Improved bone ingrowth and fixation with a thin calcium phosphate coating intended for complete resorption

et al. 2007

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Bonit is claimed to be a resorbable electrochemically deposited calcium phosphate coating consisting mainly of brushite, which is a hydroxyapatite precursor. This study involved a comparison of Ti6Al4V screw-shaped implants with and without a 15 +/- 5 microm Bonit coating in rabbit tibia and femur, after 6 and 12 weeks of insertion. The biomechanical removal torque test showed significantly increased values for the coated implants after 12 weeks (p < 0.05) but not after 6 weeks of integration. Higher bone-implant contact was found for the coated implants in the tibia after 6 weeks and for both tibial and femoral screws after 12 weeks (p < 0.05). There was no difference in the inflammatory reaction around the implants, and possible grains of the coating could be detected after 6 weeks, but not after 12 weeks of follow-up. This unloaded short-term study has shown promising results for the easily applicable and resorbable coat (Bonit) compared to uncoated titanium-alloy implants.

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Section: Discussionmentioning

confidence: 99%

Improved bone ingrowth and fixation with a thin calcium phosphate coating intended for complete resorption

et al. 2007

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“…7,8 In the similar in vivo test, mechanical failure was noted to occur at the same location in the push-out tests. 4,9,10 One of the reasons HAC delaminates from the metal implant is the insufficient adhesion between the ceramic material and the substrate. 7 In addition to the HAC degradation, the in-plane compressive stress existing at the implant surface might induce the through-thickness tensile stress that is likely to weaken the adhesion between the HAC and Ti substrate.…”

Section: Introductionmentioning

confidence: 99%

Mechanical properties and Young's modulus of plasma‐sprayed hydroxyapatite coating on Ti substrate in simulated body fluid

Yang

Chang

Lee

2003

J Biomedical Materials Res

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This study evaluated the Young's modulus, residual stress and strain, bonding strength, and microstructure of the plasma-sprayed hydroxyapatite coating (HAC) on Ti6Al4V substrate with and without immersion in Hank's balanced salt solution (HBSS). The purpose was to explore the possible correlation of HAC durability and mechanical properties of the coating. The results show that the residual stress and strain, Young's modulus, and bonding strength of the HAC after immersion in HBSS are substantially decreased. The decayed Young's modulus and mechanical properties of HACs are accounted for by the degraded interlamellar or cohesive bonding in the coating due to the increased porosity after immersion that weakens the bonding strength of coating and substrate system. The biologic implications of the research are discussed in detail. This study contributes to the arguments that the method to alleviate the dissolution of HAC will increase the bonding strength of the coating system after immersion, which together with the controlled residual stress and strain in the coating might promote the long-term stability of the HA-coated implant.

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“…Porous titanium has been used to anchor implants through bone growth into the porous structure [4][5][6][7] . This bone ingrowth provides a strong implant/bone bond [8][9][10][11] , and the pores may be interconnected threedimensionally to provide enough space for the attachment and proliferation of new bone tissues and to facilitate the transport of body fluids 1,12 . These porous structures have many applications ranging from spinal fixation to acetabular hip prostheses 5,13 , dental implants, permanent osteosynthesis plates 13 , and intervertebral discs 5 .…”

Section: Introductionmentioning

confidence: 99%

Porous titanium scaffolds produced by powder metallurgy for biomedical applications

et al. 2008

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Porous titanium scaffolds are promising materials for biomedical applications such as prosthetic anchors, fillers and bone reconstruction. This study evaluated the bone/titanium interface of scaffolds with interconnected pores prepared by powder metallurgy, using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Porous scaffolds and dense samples were implanted in the tibia of rabbits, which were subsequently killed 1, 4, and 8 weeks after surgery. Initial bone neoformation was observed one week after implantation. Bone ingrowth in pores and the Ca/P ratio at the interface were remarkably enhanced at 4 and 8 weeks. The results showed that the interconnected pores of the titanium scaffolds promoted bone ingrowth, which increased over time. The powder metallurgy technique thus proved effective in producing porous scaffolds and dense titanium for biomedical applications, allowing for adequate control of pore size and porosity and promoting bone ingrowth.

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Effect of hydroxyapatite coating on bony ingrowth into grooved titanium implants

Cited by 8 publications

References 2 publications

Improved bone ingrowth and fixation with a thin calcium phosphate coating intended for complete resorption

Improved bone ingrowth and fixation with a thin calcium phosphate coating intended for complete resorption

Mechanical properties and Young's modulus of plasma‐sprayed hydroxyapatite coating on Ti substrate in simulated body fluid

Porous titanium scaffolds produced by powder metallurgy for biomedical applications

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