Effect of hunger strike on electrocardiographic parameters

Hobikoglu, Gultekin; Urumdaş, Mehmet; Özkurt, Yalçın; Zehi̇r, Regayip; Güner, Ahmet

doi:10.5543/tkda.2018.57794

Cited by 1 publication

(1 citation statement)

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“…Contrary findings were revealed previously which analyzed the influence of brief and transient fasting on ECG parameters as well as HRV data, whereas decreased measurements for QRS duration, baseline HR and changes in QTc duration as well as HRV alterations could be revealed [ 27 , 30 , 31 ]. Additionally, the presence of transient ER pattern, QRS shortening as well as decreased HR have been reported in subjects with food deprivation [ 32 , 33 ]. The substantial impact of fasting on ECG parameters with a certain intersubjective variability of physiological response by food intake, demonstrated in previous research [ 30 ], can be confirmed by our data on ECG parameter changes.…”

Section: Discussionmentioning

confidence: 99%

Effects of Different Fasting Interventions on Cardiac Autonomic Modulation in Healthy Individuals: A Secondary Outcome Analysis of the EDIF Trial

Zimmermann

Herz

Karl

et al. 2023

Biology

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The impact of a fasting intervention on electrocardiographic (ECG) time intervals and heart rate variability (HRV) is a focus that is scarcely analyzed. The main focus of these secondary outcome data was to describe the impact of a different fasting intervention on ECG and HRV analyses. Twenty-seven healthy individuals participated in this study (11 females, aged 26.3 ± 3.8 years, BMI 24.7 ± 3.4 kg/m2), including a pre-intervention controlled run-in period. Participants were randomized to one of the three fasting cohorts: (I) alternate day fasting (ADF, n = 8), (II) 16/8 fasting (16/8 h of fasting/feasting, n = 11) and (III) 20/4 fasting (20/4 h of fasting/feasting, n = 8). An analysis of baseline ECG parameters and HRV parameters following different fasting interventions demonstrated the safety of these interventions without impacting on heart rate variability parameters during Schellong-1 testing, and revealed comparable preserved autonomic cardiac modulation (ACM) independently of the fasting intervention. In conclusion, different short-term fasting interventions demonstrated no safety ECG-based concerns and showed comparable ACM based on ECG and HRV assessments. Finally, our research topic might strengthen the scientific knowledge of intermittent fasting strategies and indicate potential clinically preventive approaches with respect to occurring metabolic disease and obesity in healthy young subjects.

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