Abstract:Urinary pyridinoline and deoxypyridinoline excretion decreases early in hormone replacement therapy, reflecting a decrease in the bone resorption rate, and no correlation was observed with the bone mass evaluated by densitometry.
“…Regarding the assessment of osteoporosis in elderly population urinary concentration of deoxypyridinoline was chosen for inexpensive, validated, easy to apply bone marker which have been identified as a good prediction by early change of bone metabolic markers of the efficacy of anti-osteoporotic drugs on bone mass in osteoporotic patients (13)(14)(15)(16). Strength exercise modalities have been showed better results in in biochemical markers of bone turnover (17,19,28) due the voluntary muscle contraction produces stress on bone morphology and the mechanical load resulting from the muscle contraction induced osteoblast formation and inhibits bone resorption (9) instead of aquatic exercises where the reduction of the gravity forces on human body when immersed in water makes and low high impact seem to be less osteogenic (29).…”
Section: Discussionmentioning
confidence: 99%
“…The deoxypyridinoline has been identified as a good prediction by early change of bone metabolic markers of the efficacy of anti-osteoporotic drugs on bone mass in osteoporotic patients (13)(14)(15)(16).…”
Objective: To determine the effect of three months of periodized hydrogymnastics exercise program on urinary concentration of deoxypyridinoline in older women. Subjects and methods: Twenty-six subjects were randomly assigned in two, intervention group (n = 16) and control group (n = 10). The intervention group followed 12-week of periodized hydrogymnastics training program five times a week, 50 minutes of water exercise with work heart rate reserve of 40-50% (1-6 th week) increasing the load to 50-60% (7-12 th week); the control group was not involved in exercise and remained sedentary. The urinary concentration of deoxypyridinoline was evaluated by high resolution liquid chromatography using the reactive immulite pyrilinks-D siemens medical solutions, pretest at the baseline and at the end post-test of the 12-week of water-exercise. As statistical analyses mixed 2 x 2 ANOVA was used, also percentage changes (Δ %) was calculated. Results: The results did not show significant improvement (p < 0.05) comparing the interaction intergroup and the measurements of urinary concentration of deoxypyridinoline (p = 0.504), percentage change (Δ %) showed positive improvements in the experimental group of -13.7 (nM/mMcreatine) in comparison with -7.1 (nM/mMcreatine) from the control group. Conclusion: The present study involves periodization increasing the load heart rate reserve of hydrogymnastics exercise in order to produce grater adaptations, but the results showed than is not possible to infer that hydrogymnastics is effective in increase urinary concentration of deoxypyridinoline in older women, will be appropriated in the future more studies to better clarify the possibilities of improvements between hydrogymnastics and urinary concentration of deoxypyridinoline. Arch Endocrinol Metab. 2015;59(6):523-7
“…Regarding the assessment of osteoporosis in elderly population urinary concentration of deoxypyridinoline was chosen for inexpensive, validated, easy to apply bone marker which have been identified as a good prediction by early change of bone metabolic markers of the efficacy of anti-osteoporotic drugs on bone mass in osteoporotic patients (13)(14)(15)(16). Strength exercise modalities have been showed better results in in biochemical markers of bone turnover (17,19,28) due the voluntary muscle contraction produces stress on bone morphology and the mechanical load resulting from the muscle contraction induced osteoblast formation and inhibits bone resorption (9) instead of aquatic exercises where the reduction of the gravity forces on human body when immersed in water makes and low high impact seem to be less osteogenic (29).…”
Section: Discussionmentioning
confidence: 99%
“…The deoxypyridinoline has been identified as a good prediction by early change of bone metabolic markers of the efficacy of anti-osteoporotic drugs on bone mass in osteoporotic patients (13)(14)(15)(16).…”
Objective: To determine the effect of three months of periodized hydrogymnastics exercise program on urinary concentration of deoxypyridinoline in older women. Subjects and methods: Twenty-six subjects were randomly assigned in two, intervention group (n = 16) and control group (n = 10). The intervention group followed 12-week of periodized hydrogymnastics training program five times a week, 50 minutes of water exercise with work heart rate reserve of 40-50% (1-6 th week) increasing the load to 50-60% (7-12 th week); the control group was not involved in exercise and remained sedentary. The urinary concentration of deoxypyridinoline was evaluated by high resolution liquid chromatography using the reactive immulite pyrilinks-D siemens medical solutions, pretest at the baseline and at the end post-test of the 12-week of water-exercise. As statistical analyses mixed 2 x 2 ANOVA was used, also percentage changes (Δ %) was calculated. Results: The results did not show significant improvement (p < 0.05) comparing the interaction intergroup and the measurements of urinary concentration of deoxypyridinoline (p = 0.504), percentage change (Δ %) showed positive improvements in the experimental group of -13.7 (nM/mMcreatine) in comparison with -7.1 (nM/mMcreatine) from the control group. Conclusion: The present study involves periodization increasing the load heart rate reserve of hydrogymnastics exercise in order to produce grater adaptations, but the results showed than is not possible to infer that hydrogymnastics is effective in increase urinary concentration of deoxypyridinoline in older women, will be appropriated in the future more studies to better clarify the possibilities of improvements between hydrogymnastics and urinary concentration of deoxypyridinoline. Arch Endocrinol Metab. 2015;59(6):523-7
Our results suggest that the tDCS technique showed small trends on postmenopausal vasomotor symptoms, justifying searches for more effective methods by which tDCS could reduce hot flashes.
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