Effect of High Influenza Activity on Risk of Ventricular Arrhythmias Requiring Therapy in Patients With Implantable Cardiac Defibrillators and Cardiac Resynchronization Therapy Defibrillators

Madjid, Mohammad; Connolly, Allison T.; Nabutovsky, Yelena; Safavi‐Naeini, Payam; Razavi, Mehdi; Miller, Charles C.

doi:10.1016/j.amjcard.2019.04.011

Cited by 49 publications

(51 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Influenza infection can trigger myocarditis (29)(30)(31), ventricular arrhythmia (32) or heart failure (33). The frequency and damage of myocardium caused by pandemic H1N1 is higher than the seasonal influenza infection (29).…”

Section: Association Between Influenza Virus Infection and Cardiovascmentioning

confidence: 99%

Immune Mechanisms in Cardiovascular Diseases Associated With Viral Infection

2020

View full text Add to dashboard Cite

Influenza virus infection causes 3-5 million cases of severe illness and 250,000-500,000 deaths worldwide annually. Although pneumonia is the most common complication associated with influenza, there are several reports demonstrating increased risk for cardiovascular diseases. Several clinical case reports, as well as both prospective and retrospective studies, have shown that influenza can trigger cardiovascular events including myocardial infarction (MI), myocarditis, ventricular arrhythmia, and heart failure. A recent study has demonstrated that influenza-infected patients are at highest risk of having MI during the first seven days of diagnosis. Influenza virus infection induces a variety of pro-inflammatory cytokines and chemokines and recruitment of immune cells as part of the host immune response. Understanding the cellular and molecular mechanisms involved in influenza-associated cardiovascular diseases will help to improve treatment plans. This review discusses the direct and indirect effects of influenza virus infection on triggering cardiovascular events. Further, we discussed the similarities and differences in epidemiological and pathogenic mechanisms involved in cardiovascular events associated with coronavirus disease 2019 (COVID-19) compared to influenza infection.

show abstract

Section: Association Between Influenza Virus Infection and Cardiovascmentioning

confidence: 99%

Immune Mechanisms in Cardiovascular Diseases Associated With Viral Infection

2020

View full text Add to dashboard Cite

show abstract

“…The results indicated that more shocks were delivered during influenza season than during other periods of the year, suggesting a correlation between higher arrhythmia burden and influenza season. The multivariate generalized linear model showed that during high influenza activity, patients were more likely to have a VA treated with shock (odds ratio [OR]: 1.06; P < .001) or ATP (OR: 1.06; P < .0001) 17 …”

Section: Introductionmentioning

confidence: 99%

“…Decompensated CHF, besides leading to hospitalization, is related to electrical myocardial homeostasis impairment, causing ventricular tachycardias (VTs) treated with shock or ATP therapy. In patients with underlying ischemic cardiomyopathy, the worsening of ischemia by increased oxygen demand and potential acute coronary syndromes led by influenza can also have a role in the increase of arrhythmic events 17 …”

Section: Introductionmentioning

confidence: 99%

Cardiac and arrhythmic complications in patients with COVID‐19

Kochi

Tagliari

Forleo

et al. 2020

Cardiovasc electrophysiol

568

517

View full text Add to dashboard Cite

In December 2019, the world started to face a new pandemic situation, the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Although coronavirus disease (COVID-19) clinical manifestations are mainly respiratory, major cardiac complications are being reported. Cardiac manifestations etiology seems to be multifactorial, comprising direct viral myocardial damage, hypoxia, hypotension, enhanced inflammatory status, ACE2-receptors downregulation, drug toxicity, endogenous catecholamine adrenergic status, among others. Studies evaluating patients with COVID-19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon. Besides, drugs currently used to treat the COVID-19 are known to prolong the QT interval and can have a proarrhythmic propensity. This review focus on COVID-19 cardiac and arrhythmic manifestations and, in parallel, makes an appraisal of other virus epidemics as SARS-CoV, Middle East respiratory syndrome coronavirus, and H1N1 influenza. K E Y W O R D S arrhythmia, COVID-19, myocardial damage, myocarditis, SARS-CoV-2 | KOCHI ET AL.

show abstract

“…High influenza activity has been reported to increase the risk of ventricular arrhythmia [68]. In a study of 121 SARS patients, tachycardia was the most common finding (72%), and other complications were hypotension (50%), bradycardia (15%), and transient paroxysmal atrial fibrillation in only one patient [69].…”

Section: Cardiac Arrhythmiamentioning

confidence: 99%

Impact of COVID-19 on the Cardiovascular System: A Review

Matsushita

Marchandot

Jesel

et al. 2020

JCM

View full text Add to dashboard Cite

The recent outbreak of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 has been declared a public health emergency of international concern. COVID-19 may present as acute respiratory distress syndrome in severe cases, and patients with pre-existing cardiovascular comorbidities are reported to be the most vulnerable. Notably, acute myocardial injury, determined by elevated high-sensitivity troponin levels, is commonly observed in severe cases, and is strongly associated with mortality. Therefore, understanding the effects of COVID-19 on the cardiovascular system is essential for providing comprehensive medical care for critically ill patients. In this review, we summarize the rapidly evolving data and highlight the cardiovascular considerations related to COVID-19.

show abstract

Effect of High Influenza Activity on Risk of Ventricular Arrhythmias Requiring Therapy in Patients With Implantable Cardiac Defibrillators and Cardiac Resynchronization Therapy Defibrillators

Cited by 49 publications

References 14 publications

Immune Mechanisms in Cardiovascular Diseases Associated With Viral Infection

Immune Mechanisms in Cardiovascular Diseases Associated With Viral Infection

Cardiac and arrhythmic complications in patients with COVID‐19

Impact of COVID-19 on the Cardiovascular System: A Review

Contact Info

Product

Resources

About