Effect of High-Induction Magnetic Stimulation on Complex Heart Rate Variability of Sus Scrofa Domesticus under General Anesthesia

Abstract

Modern approaches to physical therapy often use electric currents induced by time-varying magnetic fields. Although some of these methods are already commonly used, and only a few studies are looking at applying particular techniques on exposed tissue. In this study, a high-induction magnetic stimulation (HIMS) was applied to the chest area to affect the electrical conduction system of the heart. The animal model Sus scrofa domesticus was used for the study. Standard methods were used to make the subsequent analysis, i.e., heart rate variability in time and frequency domain. Concerning the nonlinear character of the electrocardiographic signal and evaluating complex variability (complexity), recurrent quantification analysis was used. The results show high resistance to a physiologically working heart, but there are also specific changes concerning complex variability. Thus, the results indicate that the HIMS application in the chest area may not pose a significant risk to healthy individuals in terms of the short-term effect of this technique on cardiac activity. However, cardiac activity is still, to some extent, affected by the HIMS application. In view of this and the fact that the study was conducted on an animal model, further research in this area would be appropriate.

Test of Complex Nanostructures as Gene Delivery System to Cardiac Cells

“…Nano-liposomes (NL) were prepared by hydration of phospholipid film method composed of N-[1-(2, 3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl-sulphate (DOTAP) and 1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine (DOPE) [1]. The suspension was extruded through polycarbonate filters (pore size of 100 nm).…”

“…The zeta potential of the cells and the zeta potentials of the modern "Trojan horse particles" (liposomes, exosomes, nanoparticles) are two key parameters, which must be tested to ideal compatibility, if there is the aim of the maximal effectivity of "Trojan soldiers" homing into the living cells. The DLS technique was previously applied primarily in order to study microorganisms, cancer cells or blood cells [1,2]. We used a Zetasizer Nano ZS analyser to analyse the zeta potential of cardiomyocytes and also for characterisation of nanoparticles/nanoliposomes conjugated with GFP vector, which can be used s delivery system into the muscle and another type of mammalian cells.…”

Effects of the High-Induction Magnetic Stimulation on Viscoelastic Properties of the Biceps Brachii

“…Therapeutic effects are dependent inter alia on the intensity of the field applied and possibly also on the frequency [1]. The High-Induction Magnetic Stimulation (HIMS) is a therapeutic method using high-intensity fields (up to 2.5 T), which produce high current density in the tissue exposed [2]. However, insufficient attention has been paid to the therapy of the locomotor apparatus with the use of the HIMS and thus, results of appropriate studies dealing with this problem are not available.…”

“…The research results available are even more restricted when considering the therapy with the use of the HIMS. However, the use of pulsed electromagnetic fields (PEMF) at different intensities and frequencies brought positive therapeutic results [3]- [6] and presented no hazard in terms of affecting the electric conduction system in the myocardium [2]. In general, the research available is particularly aimed at low-intensity fields in the therapy of joints, e.g.…”

Special Issue “Selected Papers from the 2019 42nd International Conference on Telecommunications and Signal Processing (TSP)”

“…Although some of these methods are already commonly used, and only a few studies are looking at applying particular techniques on exposed tissue. In the last study of the Special Issue [12], written by L. Hanáková et al, a high-induction magnetic stimulation (HIMS) was applied to the chest area to affect the electrical conduction system of the heart. The animal model Sus scrofa domesticus was used for the study.…”