Effect of high-dose finasteride combined with transurethral plasmakinetic resection of prostate on prostatespecific antigen and inflammatory factors in patients with benign prostatic hyperplasia

Abstract

Purpose: To ascertain the effect of perioperative application of high-dose of finasteride on prostatespecific antigen (PSA) in serum, tumor necrosis factor α (TNF-α) and interleukin-1β (IL-1β) in prostatic fluid of prostatic hyperplasia (BPH) patients with transurethral plasmakinetic resection of prostate (PKRP). Methods: In total, 141 BPH patients treated with PKRP in Hunan Provincial (r = 0.817, 0.838, 0.859, p < 0.001