Effect of Heated Humidification on Adherence to Continuous Positive Airway Pressure Therapy in Subjects With Obstructive Sleep Apnea and Nasopharyngeal Symptoms

Abstract

Numerous studies have demonstrated the efficacy of CPAP therapy for reducing symptoms (eg, daytime sleepiness), improving quality of life (QOL), reducing the risk of driving and occupational accidents, and preventing sequelae of obstructive sleep apnea (OSA), such as cardiovascular morbidity and mortality. [1][2][3] Many patients have trouble complying with CPAP therapy even though it is effective. 4 As many as 46 -73% of patients undergoing nasal CPAP therapy report considerable local persistent side effects, such as congestion, burning, sneezing, or dryness, 5,6 which can impair adherence to the therapy. 7 As a result, patients perceive that the therapy will cause problems and consequently refuse it. Therefore, interventions to treat these side effects could improve adherence and provide better QOL.Heated humidification was developed for patients undergoing CPAP who experience chronic nasal congestion. 4 The palatal seal, by which the uvula closes the nasopharynx, is not always complete during CPAP, leading to leaks. 5 Mouth leaks during CPAP therapy seem to be particularly