An investigation has been carried out to study the combined impacts of thermal radiation, viscous dissipation, ohmic heating, and diffusion thermo on unsteady MHD natural convective rotating secondgrade fluid past a semi-infinite vertical plate with Hall and ion-slip currents. In this study, velocity slip boundary conditions are considered. To enhance the energy equation by incorporating the effects of thermal radiation, viscous dissipation, ohmic heating, and diffusion thermo. The governing partial differential equations are converted into ordinary differential equations by using suitable nondimensional variables to solve these equations analytically, thereby adopting the familiar perturbation technique. The impacts of relevant parameters on velocity, temperature, and concentration are illustrated diagrammatically and explained in detail. Shear stress, Nusselt number, and Sherwood number are also calculated for engineering purposes and are expressed in a tabular form.