Abstract:1. Before the onset of hypertension low frequency (0.04-0.1 Hz) MAP fluctuations are reduced in SHR when compared to WKY. We studied the effect of haemorrhage under (YI blockade or angiotensin converting enzyme inhibition (CEI) on the power spectra (PS) of each strain.2. MAP was recorded from the caudal artery in conscious, 1 month old SHR and WKY. Three groups of rats were studied. Group 1, acute 2 mL haemorrhage; groups 2 and 3, injection of prazosin (0.25-2.5 mg/kg) or captopril(O.5-4 mg/kg), followed by ha… Show more
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