“…Drugs such as busulfan, a member of alkylating agents, may be used to prepare the patients who are going to receive hematopoietic stem cell transplantation. In patients undergoing hematopoietic stem-cell transplantation treated with busulfan, GSTA1*B promoter haplotype (defined by rs3957357 and rs3957356) was related to exposure variability [ 6 ]. This gene encodes for glutathione s-transferase (GST) A1 (GSTA1) isoform, the predominant GST isoform catalyzing busulfan metabolism ( ).…”