Effect of GST polymorphisms on As levels of placental and maternal biological samples

Aliyev, Vügar; Kayaaltı, Zeliha; Kaplan, Birsen; Söylemezoğlu, Tülın

doi:10.1016/j.toxlet.2012.03.261

Cited by 7 publications

(6 citation statements)

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“…The method developed by Aliyev et al in 2012 was used for preparing the samples for analysis . One milliliter of amniotic fluid samples was placed into high‐temperature‐resistant Teflon tubes in a microwave oven, and 5 mL Suprapur (Merck, Darmstadt, Germany) nitric acid (HNO 3 ) and 5 mL ultrapure water were added.…”

Section: Methodsmentioning

confidence: 99%

Amniotic fluid levels of selected trace elements and heavy metals in pregnancies complicated with neural tube defects

Ovayolu

Ovayolu²,

Karaman

et al. 2019

Congenital Anomalies

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The aims of this study were to determine the levels of trace elements and heavy metals, namely aluminum (Al), chromium (Cr), manganese (Mn), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), molybdenum (Mo), cadmium (Cd), tin (Sn), antimony (Sb), mercury (Hg), and lead (Pb), in the amniotic fluid of pregnant women, and to investigate their relationship with neural tube defects (NTDs). The study included 36 pregnant women whose fetuses were complicated with NTDs (study group) and 39 pregnant women with unaffected healthy fetuses (control group), who were matched for body mass index and gestational weeks. The amniotic fluid levels of trace elements and heavy metals were measured using inductively coupled plasma‐mass spectrometry and compared between the two groups. Significantly lower mean levels of Zn and Mo and significantly higher levels of Al, Sn, Sb, and Hg in the study group than in the healthy control group were observed, which implied that these elements are possibly correlated with risk factors for the occurrence of NTDs. In contrast, there were no significant differences in the levels of Cr, Mn, Co, Ni, Cu, As, Cd, and Pb between the groups (P ≥ .05).

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Section: Methodsmentioning

confidence: 99%

Amniotic fluid levels of selected trace elements and heavy metals in pregnancies complicated with neural tube defects

Ovayolu

Ovayolu²,

Karaman

et al. 2019

Congenital Anomalies

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“…For lead analysis we took 1 mL of the whole blood sample, placed in a Teflon tube, added 5 mL of suprapuregrade 65% nitric acid (HNO 3 , Merck, Darmstadt, Germany) and 5 mL of ultrapure water (Millipore Direct-Q3, Merck), and digested in a Milestone Start D microwave digestion system (Sorisole, Italy). The digested samples were then transferred to 50 mL polypropylene tubes, added deionised to obtain the total volume of 20 mL, and stored at +4 °C until analysis (26). Lead levels were determined with inductively coupled plasma mass spectrometry (ICP-MS; iCAP Qc model, Thermo Scientific, Waltham, MA, USA).…”

Section: Collection Of Biological Samples and Laboratory Analysismentioning

confidence: 99%

The effects of occupational lead exposure on selected inflammatory biomarkers

Türksoy

Tutkun

İritaş

et al. 2019

Archives of Industrial Hygiene and Toxicology

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In exposure to toxic metals such as lead, determining lead and cytokine levels (IL-6, IL-10, and TNF-α) is essential for early detection of diseases. The aim of this study was to develop an model for early detection of inflammation and onset of atherosclerosis in the absence of clinical findings in young workers, which could help physicians take timely an action and start treatment. This study included 49 metal workers exposed to lead occupationally and 50 unexposed administrative workers (controls) who underwent immunological analysis for cytokines (IL-6, IL-10, and TNF-α) and atherosclerosis markers (h-FABP and VCAM-1), toxicological analysis for lead, and routine biochemical analysis (ALT, AST, creatinine) at the Ankara Occupational and Environmental Diseases Hospital in 2017. Lead levels correlated with IL-6, IL-10, and TNF-α (r=0.469, r=0.521 and r=0.279, respectively, p<0.01) but did not significantly affect h-FABP and VCAM-1 levels.

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“…The samples were transferred to 50 mL polypropylene tubes, and the total volume was completed to 20 mL with ultrapure water. 17 The selenium levels of the digested samples in the microwave system were determined by the Inductively Coupled Plasma- Mass Spectrometry (ICP-MS) system; Thermo Scientific ICAP QC, USA). The operating parameters were set as follows: RF power 1550 W, nebulizer gas 0.90 L/min, plasma gas 0.80 L/min, nebulizer pressure 3.00 bar, dwell time 0.01, and spray chamber temperature 2.7 °C.…”

Section: Methodsmentioning

confidence: 99%

The Relationship between Iodine and Selenium Levels with Anxiety and Depression in Patients with Euthyroid Nodular Goiter

Turan¹,

Karaaslan²

2020

Oman Med J

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Objectives Selenium and iodine are essential microelements for normal body functions. These two elements play important roles in thyroid metabolism. The potential relationship between thyroid diseases and mental disorders have been demonstrated. We aimed to investigate the relationship between selenium and iodine levels with anxiety and depression in patients with euthyroid nodular goiter (ENG). Methods In this cross-sectional study, we enrolled 102 consecutive patients with ENG who attended the endocrine outpatient clinic between January 2018 and June 2018. We noted the patient’s demographics, thyroid ultrasound imaging, thyroid hormones, and urinary iodine concentration (UIC) results. We also obtained venous blood samples for serum selenium measurement. The same psychiatrist completed the Beck Anxiety Inventory (BAI) and Hamilton Depression Rating Scale (HDRS) for all participants. The study population was dichotomized according to the median values of selenium levels and UIC. Results BAI and HDRS scores were significantly higher in the low selenium group than the high selenium group ( p = 0.032 and p = 0.042, respectively). BAI scores were significantly higher in the low UIC group than the high UIC group ( p = 0.007). Conclusions Low selenium and UIC levels may contribute to the development of anxiety and depression, independent of thyroid functions, in patients with ENG. In these patients, selenium and iodine replacement may be useful for the prevention of anxiety and depression, especially in deficient regions.

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Effect of GST polymorphisms on As levels of placental and maternal biological samples

Cited by 7 publications

References 0 publications

Amniotic fluid levels of selected trace elements and heavy metals in pregnancies complicated with neural tube defects

Amniotic fluid levels of selected trace elements and heavy metals in pregnancies complicated with neural tube defects

The effects of occupational lead exposure on selected inflammatory biomarkers

The Relationship between Iodine and Selenium Levels with Anxiety and Depression in Patients with Euthyroid Nodular Goiter

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