Effect of graft patency on the prediction of myocardial viability by dobutamine stress and myocardial contrast echocardiography before coronary artery bypass surgery

Liu, Chang; Xiu, Chunhong; Xiang-sheng, Xiao; Ni, Lixin; Liu, Zonghong; Wang, Baichun; Shen, Jing-xia; Zhu, Kai; Zhang, Guowei; Xu, Lei; Liu, Hongyu

doi:10.1002/jcu.22045

Cited by 4 publications

(2 citation statements)

References 36 publications

(49 reference statements)

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“…This requires imaging techniques to accurately capture the peak time and peak e ciency of myocardial lling simultaneously. The results of CFR measured by AS-MCE are in good agreement with those obtained by PET imaging and CAG [19] . Coronary artery velocity reserve is also measured using the Doppler technique, which ranges from 66-100% depending on machine generation and contrast agent use, with 89% of examinations considered to be of high quality.…”

Section: Discussionsupporting

confidence: 81%

Adenosine stress myocardial contrast echocardiography combined with myocardial work function in patients with ischemia and nonobstructive coronary artery disease

ZHANG,

LI,

et al. 2024

Preprint

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Objective To evaluate the abnormal myocardial perfusion in patients with INOCA using adenosine-stressed myocardial contrast echocardiography (AS-MCE) combined with myocardial work (MW). Methods A total of 102 patients who underwent coronary angiography (CAG) or Coronary Artery CT Angiography (CCTA) for chest pain in Shaanxi Provincial People's Hospital from January 2022 to January 2024 were enrolled, those with normal results were then examined by AS-MCE, and 42 patients with INOCA results were classified as the INOCA group, while 30 normal results were classified as the control group. Conventional parameters were measured by two-dimensional echocardiography, left ventricular ejection fraction (Simpson's method) was measured, and the global longitudinal strain (GLS) and MW parameters of the left ventricle were analyzed by the Echo PAC (version 203) workstation. The myocardial perfusion parameters: peak signal intensity (A-value), curve upward slope (β value) and A×β value (reflecting myocardial blood volume) were obtained by analyzing the perfusion parameters of each group of all subjects under rest and stress states using QLab software, and the differences between the above two groups were compared. Results The INOCA group and the control group did not show significant differences in gender, age, heart rate, weight, height, body surface area, prevalence of hypertension and diabetes, hyperlipidemia, alcohol history, smoking history, and conventional ultrasound parameters such as left atrial diameter, left ventricular end-systolic and end-diastolic diameters and volumes, LVEF, diastolic mitral valve velocity, E/A, e, EDT, E/e, MW parameters, and A-value, β-value, and A-× β value at rest (P>0.05, Table 1). However, after hypertension medication, the parameters in the INOCA group decreased significantly compared to those in the control group, and the β-value in the INOCA group was significantly lower than that in the control group at rest (P<0.05). Conclusion Compared to myocardial work, adenosine-stressed myocardial echocardiography is more suitable for the clinical diagnosis of ischemia with non-obstructive coronary artery disease and its application is worthy of clinical practice promotion.

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Section: Discussionsupporting

confidence: 81%

Adenosine stress myocardial contrast echocardiography combined with myocardial work function in patients with ischemia and nonobstructive coronary artery disease

ZHANG,

LI,

et al. 2024

Preprint

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“…RT-MCE can be used to evaluate regional myocardial perfusion and coronary microvascular integrity. Nowadays, RT-MCE is conventionally used in clinical practice to detect significant angiographic CAD and to assess myocardial viability ( 12 , 13 ). The parameters calculated from RT-MCE are useful in assessing CM dysfunction with indices, such as A for myocardial blood flow volume (MBV), β for myocardial blood flow (MBF) velocity, and A×β for mean MBF ( 14 , 15 ).…”

Section: Introductionmentioning

confidence: 99%

The value of real-time myocardial contrast echocardiography for detecting coronary microcirculation function in coronary artery disease patients

Sun¹,

Wang²,

Xu³

et al. 2018

Anatol J Cardiol

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Objective:The aim of this study was to evaluate the value of real-time myocardial contrast echocardiography (RT-MCE) for detecting coronary microcirculation (CM) function in coronary artery disease (CAD) patients.Methods:Sixty-five consecutive patients were divided into CAD (n=52) and no-CAD (n=13) groups using coronary angiography (CAG). All patients underwent RT-MCE at rest and CAG within 1 week after RT-MCE. The ventricular segments in CAD patients were divided semi-quantitatively into ischemic and non-ischemic myocardial groups based on RT-MCE images. Myocardial blood volume (A), myocardial blood flow velocity (β), and mean myocardial blood flow (A×β) were obtained. The Gensini scores were calculated for CAD patients. The receiver operating characteristic (ROC) curve areas of A, β, and A×β were calculated to assess CM function in CAD patients.Results:A total of 798 and 204 segments were investigated in the CAD and non-CAD groups, respectively. In CAD patients, 332 ischemic and 466 non-ischemic segments were identified. The values of A, β, and A×β were significantly different among non-CAD, CAD, ischemic, and non-ischemic groups. ROC curve areas of A, β, and A×β were 0.85, 0.79, and 0.83, respectively, and significant differences were observed in these values among three Gensini score groups of the CAD patients.Conclusion:Varying degrees of CM function deterioration was observed in CAD patients both in ischemic and non-ischemic areas, with the deterioration being more sever in the former.

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Viabilidad miocárdica por ecocardiografía

Piñeiro¹,

Cuenca²

2019

Revista Colombiana de Cardiología

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Effect of graft patency on the prediction of myocardial viability by dobutamine stress and myocardial contrast echocardiography before coronary artery bypass surgery

Abstract: Preoperative LD-DSE and MCE ability to predict MV depends on the patency of CABG.

Cited by 4 publications

References 36 publications

Adenosine stress myocardial contrast echocardiography combined with myocardial work function in patients with ischemia and nonobstructive coronary artery disease

Adenosine stress myocardial contrast echocardiography combined with myocardial work function in patients with ischemia and nonobstructive coronary artery disease

The value of real-time myocardial contrast echocardiography for detecting coronary microcirculation function in coronary artery disease patients

Viabilidad miocárdica por ecocardiografía

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