Effect of GnRH analogue administration on Day 7 after natural mating on formation accessory corpus luteum, progesterone concentration and conception rate in llamas ( Lama glama )

Abalos, Marcos C.; Acuña, Francisco Arguedas; Cancino, Andrea Karina; Aller, Juan F.

doi:10.1016/j.anireprosci.2018.01.006

Cited by 8 publications

(7 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A previous study performed in llamas has reported that the injection of a GnRH analogue on Day 7 after natural mating was useful to induce an accessory CL formation [21]. However, plasma P4 concentration, which was evaluated only on Days 7 and 14 post-mating, did not show significant differences between treated and control groups.…”

Section: Discussionmentioning

confidence: 78%

“…Similarly, in sheep, the administration of hCG some days post-mating induced the development of an accessory CL accompanied by an increase in plasma P4 concentration [18,19,20]. In llamas, the development of an accessory CL has been achieved by the administration of a GnRH analog on day 7 post-mating [21]. However, these authors have not found an increase in plasma P4 concentration on Day 14 post-mating nor an improvement in pregnancy rates.…”

Section: J O U R N a L P R E -P R O O Fmentioning

confidence: 99%

See 1 more Smart Citation

Effect of hCG administration on Day 7 post-mating on accessory corpus luteum development and progesterone concentration in llamas

et al. 2022

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 78%

Section: J O U R N a L P R E -P R O O Fmentioning

confidence: 99%

Effect of hCG administration on Day 7 post-mating on accessory corpus luteum development and progesterone concentration in llamas

et al. 2022

View full text Add to dashboard Cite

“…The secretion of gonadotropin-releasing hormone (GnRH) is inhibited, resulting in low levels of follicle-stimulating hormone (FSH) and LH. Hence, the development of follicles is blocked, causing apathy in yaks [ 13 14 15 ]. Yak lactation can cause prolonged periods of postpartum anestrus.…”

Section: Introductionmentioning

confidence: 99%

Transcriptome and proteome analysis of pregnancy and postpartum anoestrus ovaries in yak

Zhou

Wang

et al. 2022

J Vet Sci

View full text Add to dashboard Cite

Background Domestic yaks are the most important livestock species on the Qinghai-Tibetan Plateau. Adult female yaks normally breed in the warm season (July to September) and enter anestrous in the cold season ( November to April ) . Nevertheless, it is unclear how ovarian activity is regulated at the molecular level. Objectives The peculiarities of yak reproduction were assessed to explore the molecular mechanism of postpartum anestrus ovaries in yaks after pregnancy and parturition. Methods Sixty female yaks with calves were observed under natural grazing in Haiyan County, Qinghai Province. Three yak ovaries in pregnancy and postpartum anestrus were collected. RNA sequencing and quantitative proteomics were employed to analyze the pregnancy and postpartum ovaries after hypothermia to identify the genes and proteins related to the postpartum ovarian cycle. Results The results revealed 841 differentially expressed genes during the postpartum hypoestrus cycle; 347 were up-regulated and 494 genes were down-regulated. Fifty-seven differential proteins were screened: 38 were up-regulated and 19 were down-regulated. The differential genes and proteins were related to the yak reproduction process, rhythm process, progesterone-mediated oocyte maturation, PI3K/AKT signaling pathway, and MAPK signaling pathway categories. Conclusions Transcriptome and proteomic sequencing approaches were used to investigate postpartum anestrus and pregnancy ovaries in yaks. The results confirmed that BHLHE40, SF1IX1, FBPX1, HSPCA, LHCGR, BMP15, and ET-1R could affect postpartum hypoestrus and control the state of estrus.

show abstract

“…The level of gonadotrophin‐releasing hormone receptor (GnRHR) mRNA in the hypothalamus is higher than that in the pineal gland, pituitary gland and ovary during oestrus of yak (Huo et al., 2018). This GnRH leads to accessory corpus luteum formation, but neither the plasma progesterone concentration nor the pregnancy rate is affected by having an accessory corpus luteum (Abalos et al., 2018; Biehl et al., 2017; Desaulniers et al., 2017; Kaim et al., 2003). The follicle‐stimulating hormone receptor ( FSHR ) mRNA expression level is higher in the pituitary gland tissue compared with luteinizing hormone receptor ( LHR ) during oestrus of yak, whereas there is low expression of FSHR and LHR mRNA in the pineal gland and hypothalamus.…”

Section: Introductionmentioning

confidence: 99%

A comparative transcriptome and proteomics study of post‐partum ovarian cycle arrest in yaks (Bos grunniens)

Huo

Zhou

et al. 2021

Reprod Domestic Animals

View full text Add to dashboard Cite

Post‐partum ovarian cycle arrest is the main factor affecting yak reproductive efficiency. There are few reports regarding the molecular regulatory mechanism of post‐partum oestrus at transcriptome and proteome levels in yaks. Our previous studies focussed on the ovaries of yaks with post‐partum ovarian cycle arrest and post‐partum oestrus yaks. In this study, RNA sequencing transcriptomic study was combined with quantitative proteomic analyses to identify post‐partum ovarian cycle‐related genes and proteins. Consequently, 1,149 genes and 24 proteins were found to be up‐ or downregulated during post‐partum oestrus. The analysis of differentially regulated genes identified three gene or protein pairs that were synchronously upregulated and no gene or protein pairs that were synchronously downregulated, suggesting that these upregulated genes may regulate the post‐partum ovarian cycle. The functional classification of these differentially expressed genes and proteins indicated their connection with the oocyte meiosis, the oestrogen signalling pathway, the progesterone‐mediated oocyte maturation and the gonadotrophin‐releasing hormone (GnRH) signalling pathway. In this study, a total of six genes and two proteins involved in the oocyte meiosis, the oestrogen signalling pathway, the progesterone‐mediated oocyte maturation and the GnRH signalling pathway were identified. The CSNK1A1, M91_09723, M91_11326, M91_21439, M91_19073, SHC2, Atf6b, M91_03062, HSPCA and calmodulin could regulate oestrus, respectively, in the post‐partum so as to control the anoestrus status.

show abstract

Effect of GnRH analogue administration on Day 7 after natural mating on formation accessory corpus luteum, progesterone concentration and conception rate in llamas ( Lama glama )

Cited by 8 publications

References 22 publications

Effect of hCG administration on Day 7 post-mating on accessory corpus luteum development and progesterone concentration in llamas

Effect of hCG administration on Day 7 post-mating on accessory corpus luteum development and progesterone concentration in llamas

Transcriptome and proteome analysis of pregnancy and postpartum anoestrus ovaries in yak

A comparative transcriptome and proteomics study of post‐partum ovarian cycle arrest in yaks (Bos grunniens)

Contact Info

Product

Resources

About