Effect of Genetic Information and Information About Caffeine Content on Caffeine Withdrawal Symptoms

Mills, Llewellyn; Dar‐Nimrod, Ilan; Colagiuri, Ben

doi:10.1038/s41598-017-08678-4

Cited by 7 publications

(12 citation statements)

References 43 publications

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“…Where past randomized experiments have demonstrated the critical role of etiology in evaluating familiar health-related conditions [22,56,57], the current study situates etiology in the context of transmission of cultural information. Past research indicates that genetic attributions lead to less favorable prognosis [20,58], but also lead to increased tolerance and sympathy toward patients [58,59], due to perceived attenuation of patient’s responsibility in having such a health condition [60].…”

Section: Discussionmentioning

confidence: 99%

Transmission of disorder and etiological information: Effects on health knowledge recollection and health-related cognition

et al. 2019

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Biased transmission of health knowledge has far-reaching effects on information reproduction and health-related cognitions. We examined whether transmissions of different types of disorder and etiological information influence recollections of health knowledge and evaluations of patients, by simulating the digital transmission of information. Transmission chains of four non-interacting persons (i.e., four generations) were formed. The first generation read three vignettes describing fictitious patients with one of three disorders (physiological, psychological, culture-bound) uniquely paired with one of three etiologies (genetic, environmental, unknown etiology). Next, they evaluated patients’ well-being, rated desired social distance, and recalled the vignettes. These written recollections replaced the original vignettes for a second-generation of participants, whose recollections were used for the third generation and so on. The framing of disorders affected recollections of etiology, in which culture-bound framings resulted in the poorest recall of etiologies. Participants also perceived the culture-bound disorder as the least serious but desired the most social distance from patients diagnosed with it, when compared to other disorders. The study showed that health information is selectively attended to and reproduced, possibly affected by perceived self-relevance. Faulty recollections and framing of disorders affect health cognitions, potentially instigating biased transmission of disorder- and patient-related narratives.

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Section: Discussionmentioning

confidence: 99%

Transmission of disorder and etiological information: Effects on health knowledge recollection and health-related cognition

et al. 2019

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“…(2) if one believes that they have consumed caffeine leads to a reduction in withdrawal symptoms when no caffeine is consumed" (Mills et al, 2017, p. 1). The study found that "participants who were told the coffee was caffeinated reported a greater reduction in withdrawal symptoms than those who were told it was decaffeinated" (Mills et al, 2017). These results could have indicated that the effects of caffeine are psychological in nature rather than physiological.…”

Section: Caffeine Withdrawalmentioning

confidence: 99%

“…Few students agreed that they experienced withdrawal symptoms without consistent caffeine intake. Mills, Dar-Nimrod, and Colagiuri (2017) reported that people who drink caffeine consistently or excessively typically exhibit withdrawal symptoms when they go without. According to the survey, this was not an issue for the majority of college students.…”

Section: What Are the Perceptions Of The Effects Of Caffeine Use Amonmentioning

confidence: 99%

College Students’ Caffeine Intake Habits and Their Perception of Its Effects

Beek¹,

Weier²,

Williams³

et al. 2019

JED

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Background: Caffeine is a highly used stimulant on college campuses. The prevalence of energy drinks, especially among the younger generations is cause for concern. Purpose: The purpose of this study was to determine the caffeine intake habits of college students and the perception of its effects. Method: The method used was quantitative, cross-sectional, with a descriptive design. The two research questions were: (1) What are the caffeine intake habits of college students? (2) What are the perceptions of the effects of caffeine use among college students? This study was conducted at a college campus in northern Indiana, USA. Participants included 120 male and female students ages 18 years and older. The health belief model was used to guide this study. Results: The study indicated that while caffeine is a commonly used stimulant across campus, overuse was not revealed. Many students reported being able to go 48-72 hours without caffeine and not experiencing withdrawal symptoms when going without it. However, most students do report that they perceive a need to decrease their use of caffeine, as caffeine use has increased since attending college. Conclusion: The review of the literature indicated that the use of caffeine was higher in younger people. However, the research completed as a part of this study from college students indicated that caffeine overuse may not be as prevalent as previously thought.

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“…Based on group sizes in two previous studies conducted in our laboratory (Mills et al, 2016(Mills et al, , 2017 and on what could realistically be expected from a study with stringent exclusion criteria that required 11 visits, we decided that 20 participants per group would be sufficient to detect differences in patterns of CWSQ scores across groups. Recruitment was halted at 15 per group due to slow sign-up rates and a need to finish the study.…”

Section: Participantsmentioning

confidence: 99%

“…When individuals addicted to a drug discontinue that drug or have their dose substantially reduced, they too expect negative effects, in the form of withdrawal symptoms (Huntley and Juliano, 2012;Zvolensky et al, 2018;Zywiak et al, 1996). Several studies have demonstrated that withdrawal symptoms are reduced when abstinent users believe they have consumed their drug of choice, independently of actual drug consumption (Darredeau and Barrett, 2010;Gottlieb et al, 1987;Juliano and Brandon, 2002;Mills et al, 2016Mills et al, , 2017. These placebo withdrawal-reduction effects indicate generally that withdrawal symptoms can be influenced by beliefs about how much of a drug has been consumed.…”

Section: Introductionmentioning

confidence: 99%

The effect of dose expectancies on caffeine withdrawal symptoms during tapered dose reduction

2018

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Background: Negative expectancies can exacerbate withdrawal symptoms via the nocebo effect. As such, information provided about dose reductions during attempts to taper a drug could contribute to withdrawal symptoms and increase the likelihood of relapse. The current study tested whether blinding participants to dose reductions during a supervised caffeine dose taper reduced these nocebo-induced withdrawal symptoms. Methods: Three groups of moderate to heavy coffee drinkers had their dose of caffeine reduced (tapered) from 300 mg per day to 0 mg over the course of five days and reported withdrawal symptoms twice daily. Groups were given differing information about how much caffeine they were receiving. An Open Reduction group was given accurate information about dose reductions. A Blind Reduction group was given no dose information whatsoever. A Deceptive Reduction group was misinformed about dose, with instructions suggesting that the dose remained on 300 mg for three days then dropped to 0 mg. Results: The Open Reduction group reported more pronounced caffeine withdrawal symptoms than the Deceptive Reduction group on the days with the greatest discrepancy between actual dose and informed dose, indicating a nocebo effect of open versus deceptive reductions. In addition, the rate of increase in reported withdrawal symptoms in the Blind Reduction and Deceptive Reduction groups was less than that of the Open Reduction group. Conclusion: These results suggest that awareness of dose reductions during a dose taper can result in a nocebo withdrawal effect, and that removing this awareness can reduce withdrawal. This has important implications for standard supervised dose-tapering practice, where patients are aware of the timing and magnitude of dose reductions.

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Effect of Genetic Information and Information About Caffeine Content on Caffeine Withdrawal Symptoms

Cited by 7 publications

References 43 publications

Transmission of disorder and etiological information: Effects on health knowledge recollection and health-related cognition

Transmission of disorder and etiological information: Effects on health knowledge recollection and health-related cognition

College Students’ Caffeine Intake Habits and Their Perception of Its Effects

The effect of dose expectancies on caffeine withdrawal symptoms during tapered dose reduction

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