Abstract:Background and aims
Non-alcoholic fatty liver disease (NAFLD) increases cardiovascular morbidity and mortality, and carries poor long-term hepatic prognosis. Data about the role of genetic and environmental factors in the hepatic lipid accumulation are limited. The aim of the study was to evaluate the genetic and environmental impact on the hepatic lipid accumulation within a cohort of adult twin pairs.
Patients and methods
We investigated 182 twin subjects [monozygotic (MZ,
n
= 114) and dizygotic (DZ,
n
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