Psychological well-being is a key feature of mental health and can be defined as pleasure, eudaimonic happiness, and resilience (coping, emotional regulation, health problem solving). To improve psychological well-being, it is useful to understand the underlaying mechanisms associated with psychological well-being. Therefore, understanding the association with psychological well-being is an important area of research. This study aimed to assess the psychological well-being status during COVID-19 pandemic and find out the association between psychological well-being status with Socio-economic condition during the COVID-19 pandemic. The study contains of 120 including 60 female and 60 male adulthood age between 20 to 60 in the Thiruvallur district of Tamil Nadu. To assess the psychological well-being the standardized tool was used developed by Ryff’s in 1995. The study result found that significant difference in personal growth (M = 18.6 and SD = 4.30) and positive relationship (M = 18.46 and SD = 4.54) of male respondents at p = 0.04. It showed that personal growth and positive relationship domain of psychological well-being status was high in male respondents than female respondents. The study also found that there was a positive co-relation between all psychological wellbeing domain (autonomy, environmental mastery, personal growth, positive relations, purpose in life, and self-acceptance) with socio-economic condition at (p = .001) level.