“…Between each dosing, there was a 1-week drug washout period. After oral drug dosing, blood samples (3.0 mL) were collected from the jugular vein at 0, 0.25, 0.5, 1, 2, 4, 6, 8, 12, 24, 36, 48, and 72 h [29]. The blood samples were immediately centrifuged for 10 min at 3000 rpm, and the plasma was stored at −70 • C until the analysis.…”