Effect of gamma sterilization on Gymnema sylvestre leaf extract fused Polycaprolactone nanofiber for effective wound dressing applications

Subramanian, Sundarapandian; Karuppannan, Sathish Kumar; Ramalingam, Raghavendra; Dowlath, Mohammed Junaid Hussain; Khalith, S.B. Mohamed; Musthafa, Shazia Anjum; Chitra, V.; Munuswamy-Ramanujam, Ganesh; Arunachalam, Kantha Deivi

doi:10.1016/j.matlet.2021.130145

Cited by 8 publications

(2 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings agree with the results reported by Subramanian et al, where sterilized PCL nanofibers containing Gymnema sylvestre leaf extract via gamma radiation. They observed that irradiation at 25 kGy did not alter the chemical structure of the nanofibers [ 52 ]. Similarly, Augustine et al based on FT-IR results, revealed that the chemical composition of PCL in electrospun membranes is preserved after irradiation at 25 kGy [ 21 ].…”

Section: Resultsmentioning

confidence: 99%

Gamma radiation effect on the chemical, mechanical and thermal properties of PCL/MCM-48-PVA nanocomposite films

Paula

Azevedo

Silva

et al. 2023

Heliyon

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Gamma radiation effect on the chemical, mechanical and thermal properties of PCL/MCM-48-PVA nanocomposite films

Paula

Azevedo

Silva

et al. 2023

Heliyon

View full text Add to dashboard Cite

“…Polycaprolactone (PCL) has a low melting temperature, a low glass-transition temperature, high thermal stability, excellent processability, excellent mechanical properties, biocompatibility, and biodegradability, and is highly permeable to a variety of drugs and easy to load with drugs, which has stimulated researchers [ 25 , 26 , 27 ]. Extensive research has been conducted on its potential applications in the biomedical field [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Novel Multifunctional Wound Dressing by Near-Field Direct-Writing Electrospinning and Its Application

Li,

Lin,

et al. 2024

Polymers

View full text Add to dashboard Cite

Near-field direct-writing electrospinning technology can be used to produce ordered micro/nanofiber membrane dressings. The application of this technology can simply realize the control of dressing porosity, compound different functional substances, and adjust their distribution, thus improving the defects of common dressings such as insufficient breathability, poor moisture retention performance, and single function. Herein, a novel multifunctional wound dressing was prepared to utilize near-field direct-writing electrospinning technology, in which calf skin collagen type I (CSC-I) and polycaprolactone (PCL) were used as the composite matrix, Hexafluoroisopropanol (HFIP) as the solvent, and erythromycin (ERY) as an anti-infective drug component. The results show that the micro/nanofiber membranes prepared by near-field direct-writing electrospinning technology can all present a complete mesh structure, excellent thermal stability, and good moisturizing properties. Moreover, the composite fiber membrane loaded with ERY not only had obvious antibacterial properties against E. coli and S. thermophilus but also a better slow-release function of drugs (it is rare to have both in traditional wound dressings). Therefore, this experimental design can provide relevant theories and an experimental foundation for preparing a new type of medical dressing with drug loading and has good guiding significance for the application and promotion of near-field direct-writing electrospinning in medical dressings.

show abstract

Gymnema sylvestre R. Br.: Phytochemicals and Medicinal Properties

Vats,

Dey,

Bhandari

et al. 2023

Medicinal and Aromatic Plants of the World

View full text Add to dashboard Cite

Effect of gamma sterilization on Gymnema sylvestre leaf extract fused Polycaprolactone nanofiber for effective wound dressing applications

Cited by 8 publications

References 13 publications

Gamma radiation effect on the chemical, mechanical and thermal properties of PCL/MCM-48-PVA nanocomposite films

Gamma radiation effect on the chemical, mechanical and thermal properties of PCL/MCM-48-PVA nanocomposite films

Preparation and Characterization of Novel Multifunctional Wound Dressing by Near-Field Direct-Writing Electrospinning and Its Application

Gymnema sylvestre R. Br.: Phytochemicals and Medicinal Properties

Contact Info

Product

Resources

About