Effect of gamma-aminobutyric acid produced by Lactobacillus sakei B2-16 on diet and exercise in high fat diet-induced Obese rats

Kook, MooChang; Cho, Seok-Cheol; Kang, Jun-Yong; Song, Young-Ju; Park, Hoon

doi:10.1007/s10068-014-0268-0

Cited by 9 publications

(6 citation statements)

References 23 publications

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“…This result may indicate that APS may have initiated the restoration of the endothelial function thereby decreasing plasma ACE activity. The reduced activity observed in hypercholesterolemic rats fed diets containing APS could be attributed to the observed inhibitory effect of both the protein and non-protein amino acids present in APS [49,59,64,36,37,77]. GABA possesses antihypertensive potential and hence may act as an ACE inhibitor.…”

Section: Discussionmentioning

confidence: 99%

Alligator pepper/Grain of Paradise ( Aframomum melegueta ) modulates Angiotensin-I converting enzyme activity, lipid profile and oxidative imbalances in a rat model of hypercholesterolemia

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Alligator pepper/Grain of Paradise ( Aframomum melegueta ) modulates Angiotensin-I converting enzyme activity, lipid profile and oxidative imbalances in a rat model of hypercholesterolemia

et al. 2016

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“…γ-aminobutyric acid γ-aminobutyric acid (GABA) is a ubiquitous non-protein amino acid and a critical component of the central nervous system, including the brain and spinal fluid; it is also the main inhibitory neurotransmitter [159]. In the human body, GABA improves blood flow, and thereby the oxygen supply, to the brain.…”

Section: Exopolysaccharidesmentioning

confidence: 99%

A Review of the Health Benefits of Kimchi Functional Compounds and Metabolites

Kim,

Kwon,

Hwang

et al. 2023

Microbiol. Biotechnol. Lett.

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Kimchi is a traditional Korean dish made with salted fermented vegetables and contains various nutrients and functional substances with potential health benefits. The fermentation process used to make kimchi creates chemical changes in the food, developing nutrients and functional substances that are more easily absorbed and enhanced by the body. Recent studies have shown that several lactic acid bacteria strains isolated from kimchi exhibit probiotic properties and have several health benefiting properties such as such as anticancer, anti-obesity, and anti-constipation; they also promote colon health and cholesterol reduction in in vitro and in vivo experiments, as well as in epidemiological cohort studies. Kimchi contains prebiotics, non-digestible fibers that nourish beneficial gut bacteria; therefore, its intake effectively provides both probiotics and prebiotics for improved gut health and a fortified gut-derived immune system. Furthermore, fermentation of kimchi produces a variety of metabolites that enhance its functionality. These metabolites include organic acids, enzymes, vitamins, bioactive compounds, bacteriocins, exopolysaccharides, and γ-aminobutyric acid. These diverse health-promoting metabolites are not readily obtainable from single food sources, positioning kimchi as a valuable dietary option for acquiring these essential components. In this review, the health functionalities of kimchi ingredients, lactic acid bacteria strains, and health-promoting metabolites from kimchi are discussed for their properties and roles in kimchi fermentation. In conclusion, consuming kimchi can be beneficial for health. We highlight the benefits of kimchi consumption and establish a rationale for including kimchi in a balanced, healthy diet.

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“…Many microorganisms can produce GABA, including bacteria, fungi, and yeasts, although lactic acid bacteria (LAB) are the most utilized GABA producers (5–8). GABA-producing LAB have been a focus of research in recent years because they possess unique physiological properties and are regarded as safe for use in the food industry (6, 9–11). Many food-derived lactobacilli produce GABA, including several strains of Lactobacillus brevis (12–16), L.…”

Section: Announcementmentioning

confidence: 99%

Genome Sequence of Lactobacillus plantarum KB1253, a Gamma-Aminobutyric Acid (GABA) Producer Used in GABA-Enriched Tomato Juice Production

Nakatani¹,

Fukao²,

Fukaya³

2019

Microbiol Resour Announc

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Effect of gamma-aminobutyric acid produced by Lactobacillus sakei B2-16 on diet and exercise in high fat diet-induced Obese rats

Cited by 9 publications

References 23 publications

Alligator pepper/Grain of Paradise ( Aframomum melegueta ) modulates Angiotensin-I converting enzyme activity, lipid profile and oxidative imbalances in a rat model of hypercholesterolemia

Alligator pepper/Grain of Paradise ( Aframomum melegueta ) modulates Angiotensin-I converting enzyme activity, lipid profile and oxidative imbalances in a rat model of hypercholesterolemia

A Review of the Health Benefits of Kimchi Functional Compounds and Metabolites

Genome Sequence of Lactobacillus plantarum KB1253, a Gamma-Aminobutyric Acid (GABA) Producer Used in GABA-Enriched Tomato Juice Production

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