Effect of Functional Fitness on Plasma Oxidation Level in Elders: Reduction of the Plasma Oxidants and Improvement of the Antioxidant Barrier

Gamberi, Tania

doi:10.11648/j.ajss.20180602.14

Cited by 7 publications

(8 citation statements)

References 22 publications

(27 reference statements)

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“…On the other hand, at the end of the training program, both a significant reduction in oxidative stress, as demonstrated by a shift of d-ROM from middle to low levels [ 30 ], as well as a substantial increase in BAP levels, which indicates a substantial improvement of the antioxidant capacity from a moderate deficiency status to an almost normal value [ 30 , 31 , 32 ], occurred. This is in line with previous literature showing that regular and adequate (age-tailored) physical activity has beneficial effects on the balance between plasma ROS production and their neutralization [ 51 , 52 , 53 ]. This represents another key point since, during aging, the body becomes more susceptible to oxidation, and intense physical activity could increase cellular ROS production, thus inducing a state of cellular damage and oxidative stress.…”

Section: Discussionsupporting

confidence: 92%

Effects of a 24-Week Exercise Program on Functional Fitness, Oxidative Stress, and Salivary Cortisol Levels in Elderly Subjects

et al. 2022

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Background and Objectives: Aging is a biological and irreversible process characterized by physiological alterations resulting in a progressive decline in biological functions, decreased resistance or adaptability to stress, and increased disease susceptibility. A decline in functional fitness, imbalance between pro- and antioxidant capacity, and/or hormonal dysregulation adversely impact physical capacity, emotional status, and overall quality of life, especially within the elderly population. On the other hand, regular physical activity is considered an effective strategy to prevent and reduce those changes associated with primary aging and concurrent chronic disease, while slowing age-related physical degeneration. However, there is still limited evidence-based information regarding both the intensity and interval of effective interventions on physical functioning in older adults. Thus, the aim of the study was to assess the effects of a 24-week regular multimodal exercise program on functional fitness, oxidative stress, salivary cortisol level, and self-perceived quality of life in a group of eighteen physically active elderly subjects (mean age 72.8 ± 7.5 years). Materials and Methods: A set of anthropometric and physical measurements (grip strength, chair sit to stand, sit and reach and back scratch) assessing the functional fitness performance were evaluated. Moreover, biochemical markers (derived-reactive oxygen metabolites (d-ROMs) and the biological antioxidant potential (BAP) tests, and salivary cortisol levels) and the EuroQoL 5-Dimension 3-Level (EuroQoL 5-D 3-L) self-perceived questionnaire of quality of life were measured before and after the intervention program. All measurements were normally distributed as assessed by D’Agostino and Pearson’s omnibus normality test. Student’s t-tests were used to evaluate the differences in all the parameters measured at baseline (T0) and after the 24-week physical program (T1). Results: The results showed that an age-tailored structured intervention exercise program (1 h per session, twice per week, for 24 weeks) was effective in improving flexibility and other biomechanical parameters, such as muscle strength and the dynamic balance fitness component, which are key to performing daily tasks independently. Moreover, biochemical analyses demonstrate that the proposed intervention program has beneficial effects on the balance between plasma ROS production and their neutralization. Conclusions: The results confirm the benefits of regular physical activity in older adults resulting in improved physical strength and flexibility in the functional fitness parameters, and in regulating anti- and pro-oxidant activity and cortisol (stress hormone) levels.

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Section: Discussionsupporting

confidence: 92%

Effects of a 24-Week Exercise Program on Functional Fitness, Oxidative Stress, and Salivary Cortisol Levels in Elderly Subjects

et al. 2022

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“…Use MHD to determine the posture [22]. e five sample sequences and the sequence to be recognized are reduced to a three-dimensional space, and five sequences S(i � 1,2, ..., 5)Λ and the sequence to be recognized S are obtained.…”

Section: H(a B) � Max(h(a B) H(b A))mentioning

confidence: 99%

Application of Virtual Reality and Artificial Intelligence Technology in Fitness Clubs

Zhao

2021

Mathematical Problems in Engineering

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With the continuous development and progress of virtual reality technology in recent years, the application of virtual reality technology in all aspects of real life is no longer limited to the military field, medical, or film production fields, but it gradually appears in front of the public, into the lives of ordinary people. The human-computer interaction method in virtual reality and the presentation effect of the virtual scene are the two most important aspects of the virtual reality experience. How to provide a good human-computer interaction method for virtual reality applications and how to improve the final presentation effect of the virtual reality scene is also becoming an important research direction. This paper takes the virtual fitness club experience system as the application background, analyzes the function and performance requirements of the virtual reality experience system in the virtual reality environment, and proposes the use of Kinect as a video acquisition device to extract the user’s somatosensory operation actions through in-depth information to achieve somatosensory control. This article adopts a real human-computer interaction solution, uses Unity 3D game engine to build a virtual reality scene, defines shaders to improve the rendering effect of the scene, and uses Oculus Rift DK2 to complete an immersive 3D scene demonstration. This process greatly reduces resource consumption; it not only enables users to experience unprecedented immersion as users but also helps people create unprecedented scenes and experiences through virtual imagination. The virtual fitness club experience system probably reduces resource consumption by nearly 70%.

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“…Another important factor to consider is the age of the participants. In fact, we recently demonstrated that functional fitness, a type of moderate training, significantly reduces PPC and enhances antioxidant efficiency in elderly [38].…”

Section: Plasma Protein Carbonylation and Exercisementioning

confidence: 99%

“…As reported by Fedorova et al 2014 [7], three methods are currently used to detect protein carbonyls. The main stages of these procedures can be summarized in: (i) biochemical and immunological techniques, were the measurement of protein plasma or muscle carbonyls was performed using immunoblot and/or ELISA Kits [8][9][10][11][12][13] (ii) spectrophotometric analyses and (iii) proteomic approaches [36][37][38][39][40][41].…”

Section: Introductionmentioning

confidence: 99%

Irreversible plasma and muscle protein oxidation and physical exercise

Gorini

Gamberi

Fiaschi

et al. 2018

Free Radical Research

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The imbalance between the reactive oxygen (ROS) and nitrogen (RNS) species production and their handling by the antioxidant machinery (low molecular weight antioxidant molecules and antioxidant enzymes), also known as oxidative stress, is a condition caused by physiological and pathological processes. Moreover, oxidative stress may be due to an overproduction of free radicals during physical exercise. Excess of radical species leads to the modification of molecules, such as proteinsthe most susceptible to oxidative modificationlipids and DNA. With regard to the oxidation of proteins, carbonylation is an oxidative modification that has been widely described. Several studies have detected changes in the total amount of protein carbonyls following different types of physical exercise, but only few of these identified the specific amino acidic residues targets of such oxidation. In this respect, proteomic approaches allow to identify the proteins susceptible to carbonylation and in many cases, it is also possible to identify the specific protein carbonylation sites. This review focuses on the role of protein oxidation, and specifically carbonyl formation, for plasma and skeletal muscle proteins, following different types of physical exercise performed at different intensities. Furthermore, we focused on the proteomic strategies used to identify the specific protein targets of carbonylation. Overall, our analysis suggests that regular physical activity promotes a protection against protein carbonylation, due to the activation of the antioxidant defence or of the turnover of protein carbonyls. However, we can conclude that from the comprehensive bibliography analysed, there is no clearly defined specific physiological role about this post-translational modification of proteins.

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Effect of Functional Fitness on Plasma Oxidation Level in Elders: Reduction of the Plasma Oxidants and Improvement of the Antioxidant Barrier

Cited by 7 publications

References 22 publications

Effects of a 24-Week Exercise Program on Functional Fitness, Oxidative Stress, and Salivary Cortisol Levels in Elderly Subjects

Effects of a 24-Week Exercise Program on Functional Fitness, Oxidative Stress, and Salivary Cortisol Levels in Elderly Subjects

Application of Virtual Reality and Artificial Intelligence Technology in Fitness Clubs

Irreversible plasma and muscle protein oxidation and physical exercise

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