Effect of Fluorinated Ligand on Structural, Electronic and DNA-binding Properties of Copper Paddlewheel Complex: Synthesis, Structure and Properties

Abstract

This paper presents synthesis, structural description and properties of a binuclear paddlewheel copper(II) carboxylate complex with formula [(py)Cu(μ-L) 4 Cu(py)], where py = pyridine and L = 4-fluorophenylacetate. Structural characteristics, electronic absorption and DNA-binding properties of the synthesized complex have been compared to those of the non-fluorinated analogues (where F is replaced by H,-CH 3 and-OCH 3) already reported and the modifications successfully ascribed to fluorine. The complex exhibits typical paddlewheel structure and there are two crystallographically independent molecules in the unit cell. The electronic absorption spectrum of complex is also different and the mode and extent of DNA-binding ability of complex are significantly altered owing to the presence of suitably substituted fluorine. The effect of fluorine is clearly manifested in the modified properties of synthesized complex.

Dinuclear Ternary Copper(II) Complex: Synthesis, Characterization, Structure and DNA-Binding Studies

“…Such elongation of the apical bond has been found typical of the previously reported complexes as well. 29 The nearly perfect square pyramidal geometry around copper has been made possible by the asymmetric nature of the Cu-O bond distance of the bridging oxygen. This Cu-O-Cu asymmetric bonding of the bridging oxygen is also typical of other copper(II) complexes.…”

A binary copper(II) complex having stepped polymeric structure: Synthesis, characterization, DNA-binding and anti-fungal studies

“…2 If both copper ions of the paddlewheel unit are coordinated axially by monodentate ligands, the resulting structure is a discrete paddlewheel molecule. 3 However, there are complexes having interlinked paddlewheel units in which the binuclear units are trans-interlinked via copper, oxygen or both atoms by intervening ligands. There is great structural diversity of such polynuclear paddlewheel complexes.…”