Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: A randomized trial

Abstract

Objectives: To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment. Materials and Methods: Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjects). The selected product was brushed on for 2 minutes twice daily for 4 months. Subjects were reviewed for 4 months on a monthly basis. The Enamel Decalcification Index (EDI) was used to determine the number of white spot lesions per surface at each visit. Results: 100 subjects (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lend strong support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus. Conclusions: The use of Clinpro 5000, Clinpro Crème, and MI paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. Clinpro 5000 has a marginally better effect than the two other test pastes. The results of this study can be used by clinicians when deciding the effectiveness of using fluoride dentifrice products to prevent white spot lesions in their orthodontic practice (ClinicalTrials.gov ID: NCT03440996).

Effect of nanosilver mouthwash on prevention of white spot lesions in patients undergoing fixed orthodontic treatment - a randomized double-blind clinical trial

“…In this study, the naked eye method was used for the evaluation of WSLs, which is clinically relevant, more feasible and used in most of the studies. 13 The visual examination of WSLs was done on the buccal surface of the upper and lower anterior teeth directly after clinical examinations. The labial surface of each tooth was divided into four areas (gingival, mesial, incisal and distal).…”

Remineralization Potential of Functionalized Tricalcium Phosphate Versus Casein Phosphopeptide- Amorphous Calcium Phosphate in Caries White Spot Lesions “A Randomized Clinical Trial”

“…A study was done in order to detect the effect of the following materials: Clinpro 5000 tooth crème, Clinpro Tooth Creme, and MI-Paste Plus on ` the formation of white spot lesions in patients undergoing orthodontic treatment the results of this study showed that the use of Clinpro 5000, Clinpro Creme, and MI paste Plus all have a reduction effect on white spot lesions that disagree with my results with superior effect to Clinpro 5000 Kau et al (2019) 25 The participant's satisfaction was primary assessed in this study because public perception is considered as the main factor that drives the demand for the esthetic dental treatment. Ensures that research outcome is patient relevant.…”

The Significance of Lactoperoxidase System in Oral Health: Application and Efficacy in Oral Hygiene Products

“…Currently, caries prophylaxis involves the use of classic fluoride preparations [187,197,198] and intensively studied nonfluoride methods including chlorhexidine [199], probiotics [200], xylitol [199,201], triclosan [202], CPP-ACP [203], and proteins of natural origin. Dentifrices with the addition of antibacterial proteins such as LPO may be an alternative to common fluoride preparations.…”