2000
DOI: 10.1067/mtc.2000.108166
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Effect of flow competition on internal thoracic artery graft: Postoperative velocimetric and angiographic study

Abstract: Competitive blood flow reduces internal thoracic artery graft flow and diameter according to the grade of the native coronary artery stenosis. These data suggest that grafting the internal thoracic artery to the coronary artery with stenosis of a low grade can cause graft atrophy and failure.

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Cited by 59 publications
(30 citation statements)
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“…Doppler studies have suggested that moderate stenosis in the target vessel is associated with competitive flow, thereby leading to decreased antegrade flow in the arterial graft, which may lead to early failure (string sign). [13][14][15] Recently, Berger et al reported that the degree of stenosis in the native vessel is a major predictor of ITA graft occlusion. 17) The ITA was anastomosed to the LAD in 96% of our recent CABG cases.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Doppler studies have suggested that moderate stenosis in the target vessel is associated with competitive flow, thereby leading to decreased antegrade flow in the arterial graft, which may lead to early failure (string sign). [13][14][15] Recently, Berger et al reported that the degree of stenosis in the native vessel is a major predictor of ITA graft occlusion. 17) The ITA was anastomosed to the LAD in 96% of our recent CABG cases.…”
Section: Discussionmentioning
confidence: 99%
“…[9][10][11][12] However, it has been suggested that mild or moderate stenosis in the LAD is associated with competitive flow, thereby leading to a decreased antegrade flow in the ITA graft, which may lead to graft failure. [13][14][15][16] The purpose of this study was to evaluate the influence of clinical parameters and the degree of LAD stenosis on postoperative ITA graft stenosis, as well as the relationship between postoperative regional ischemia of the LAD territory, as assessed by adenosine thallium-201 myocardial perfusion scintigraphy (Tl-201-MPS), and postoperative ITA graft stenosis using 320-ADCT.…”
Section: Introductionmentioning
confidence: 99%
“…atvejų iki operacijos atliktos koronarografijos metu didžiausias susiaurėjimas buvo tik 50-60 proc. Panašius duomenis pateikė kitų naujausių tyrimų autoriai, kurie nurodo, kad dažnesniam vidinės krūtinės arterijos (arterinės jungties) užsidarymui didelę įtaką daro nedidelio laipsnio susiaurėjimas tiek priekinėje tarpskilvelinėje šakoje (p<0,05), tiek dešinėje vainikinėje arterijoje (p<0,005) (17)(18)(19). Veninių jungčių pratekamumas nėra stabilus dydis, bet palaipsniui mažėjantis ir labiau priklausomas nuo aterosklerozinio proceso progresavimo tiek vainikinėse arterijose, tiek naujai suformuotose jungtyse (20)(21)(22).…”
Section: Rezultatai Ir Jų Aptarimasunclassified
“…Invasive studies have shown that residual flow in the recipient artery, when the obstruction is not severe, can compete with the flow of the patent LITA, thereby reducing blood flow in the graft. In addition, collateral circulation resulting from the total obstruction of a vessel, also called a physiological bridge, can lead to flow competition within the LITA bypass [18]. As the coronary disease progress es in the native or collaterals, the flow of the graft increases considerably.…”
Section: Dvti = Diastolic Average Velocity-time Integral; Df = Diastomentioning
confidence: 99%
“…Even so, Shimizu et al [18] and Dubey et al [19] have shown that the graft diameter, its degree of obstruction, and its flow, are proportional to DPV [20]. A DPV/SPV ratio greater than 1 [21] is associated with good angiographic findings and can provide sensitivity up to 100% and a specificity of 58% for detecting graft patency [12].…”
Section: Dvti = Diastolic Average Velocity-time Integral; Df = Diastomentioning
confidence: 99%