Effect of flaxseed lignan on the dynamics of <i>Lactiplantibacillus plantarum</i> and starter cultures in fermented milk

Thomas, Elizabeth; Panjagari, Narender Raju; Ganguly, Sangita; Rashmi, Hogarehalli Mallappa; P.V, Swetha Damodharan; Singh, Ashish Kumar

doi:10.1111/ijfs.16466

Cited by 2 publications

(2 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our previous research describes the extraction of SDG by direct alkaline hydrolysis coupled with magnetic stirring, microwave, and ultrasound; HPLC and FTIR estimation of SDG from defatted whole flaxseed and hull; and their effect on starter and probiotic culture [19]. Briefly, SDG was extracted from milled defatted flaxseed flour using direct alkaline hydrolysis coupled with magnetic stirring.…”

Section: Development Of Flaxseed Lignan-enriched Set Dahimentioning

confidence: 99%

“…The total viable count and probiotic count of SDG-enriched dahi were not significantly different from those of the control (p > 0.05). A thorough investigation of the effects of SDG on Lactiplantibacillus plantarum and starter cultures found that flaxseed lignan did not impact their fermentation dynamics [19].…”

Section: Physico-chemical Textural Sensory and Microbiological Attrib...mentioning

confidence: 99%

See 1 more Smart Citation

Development and Validation of Flaxseed Lignan-Enriched Set-Type Fermented Milk to Manage Postmenopausal Osteoporosis

Thomas,

Panjagari,

Ganguly

et al. 2024

Fermentation

Self Cite

View full text Add to dashboard Cite

A functional set dahi (fermented milk analogous to yoghurt) with a desirable probiotic (Lactiplantibacillus plantarum A5) count of 9.36 log CFU/mL and excellent techno-functional attributes (DPPH: 41.95% RSA, firmness: 485.49 g, sensory overall acceptability: 8.51) was developed to contain 260 mg of SDG in 20 g of dahi. Twenty-four female Albino Wistar rats (3 months old, >180 g) were ovariectomized (OVX) and divided into three groups: OVX control, OVX and control dahi, and OVX and SDG-enriched dahi. The animal study found that ovariectomy decreased serum calcium, oestrogen, and bone ash calcium levels by 32.27, 30.95, and 48.46 percent, respectively, compared to the sham group (n = 8), while daily administration of SDG-enriched dahi (20 g) for eight weeks restored them. The proximal tibial metaphysis and distal femoral epiphysis micro-CT study showed that the ovariectomy lowered bone mineral density (BMD) by 11.06% and 9.18%, respectively, and lowered Trabecular thickness (Tb. Th) by 12.66% and 11.86%, respectively, while increasing Trabecular separation (Tb. Sp.) by 90.69% and 87.70%, respectively, compared to the sham control-group rats. SDG-enriched dahi improved BMD by 16.06 and 12.24% and Tb. Th by 35.32 and 19.62%, respectively, and decreased Tb. Sp by 47.04 and 47.22%, respectively, in OVX rats. The results suggest that the developed set dahi may help treat postmenopausal osteoporosis.

show abstract

Section: Development Of Flaxseed Lignan-enriched Set Dahimentioning

confidence: 99%

Section: Physico-chemical Textural Sensory and Microbiological Attrib...mentioning

confidence: 99%

Development and Validation of Flaxseed Lignan-Enriched Set-Type Fermented Milk to Manage Postmenopausal Osteoporosis

Thomas,

Panjagari,

Ganguly

et al. 2024

Fermentation

Self Cite

View full text Add to dashboard Cite

show abstract

Flaxseed Derived Secoisolariciresinol diglucoside Enriched Fermented Milk Exhibits Antiosteopenic Effects in Ovariectomized Rats

Thomas

Panjagari

Ganguly

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

The current research aims to validate the effect of flaxseed lignan (secoisolariciresinol diglucoside (SDG)) enriched dahi (analogues to yoghurt) in preventing menopausal osteoporosis in-vivo using an ovariectomized (OVX) rat model. Forty female Albino Wistar rats (3 months old, > 180 g) were divided into sham, OVX control, OVX + control dahi, OVX + SDG enriched dahi groups (n = 8). The results of the animal study indicated the serum calcium and estrogen levels and the bone ash calcium were decreased by 32.27%, 30.95% and 48.46% respectively after ovariectomy, compared to the sham group. The administration of the control dahi increased the serum calcium and estrogen levels as well as the bone ash calcium by 6.26%, 38.62% and 44.57%, while, the daily administration of the SDG enriched dahi (20 g, ~ 260 mg SDG) for eight weeks increased them by 37.37%, 85.52% and 82.34%, respectively, compared to OVX group. The micro-CT analysis of proximal tibial metaphysis region revealed that the ovariectomy decreased the bone mineral density (BMD) and trabecular thickness (Tb.Th) by 11.06% and 90.69%, while the trabecular separation (Tb.Sp.) was increased by 90.69% compared to the sham control group rats. The administration of the control dahi increased the BMD and Tb.Th by 8.85% and 10.04%, and decreased Tb.Sp by 22.13%, whereas the supplementation of SDG enriched dahi increased them by 13.84% and 26.10%, respectively and decreased the Tb.Sp by 88.82% compared to OVX rats. Similar results were obtained in the micro-CT analysis of distal femur epiphysis region. Hence, based on the above results, it could be concluded that the developed product could be useful in alleviating postmenopausal osteoporosis.

show abstract

Effect of flaxseed lignan on the dynamics of Lactiplantibacillus plantarum and starter cultures in fermented milk

Cited by 2 publications

References 28 publications

Development and Validation of Flaxseed Lignan-Enriched Set-Type Fermented Milk to Manage Postmenopausal Osteoporosis

Development and Validation of Flaxseed Lignan-Enriched Set-Type Fermented Milk to Manage Postmenopausal Osteoporosis

Flaxseed Derived Secoisolariciresinol diglucoside Enriched Fermented Milk Exhibits Antiosteopenic Effects in Ovariectomized Rats

Contact Info

Product

Resources

About