Effect of Flavonoids on Mutagenicity and Bioavailability of Xenobiotics in Foods

Stavrić, B.; Ti, Matula; Klassen, R.; Rh, Downie; Rj, Wood

doi:10.1021/bk-1992-0507.ch017

Cited by 19 publications

(15 citation statements)

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“…Kaempferol and quercetin are potent quenchers of ROO • , O 2 , and 1 O 2 (44). Quercertin and other polyphenols have been shown to play a protective role in carcinogenesis by reducing the bioavailability of carcinogens (45). Quercetin, with 3′,4′-dihydroxy substitution in the B-ring and conjugation between the A-and B-rings, has a high antioxidant potential (46).…”

Section: Resultsmentioning

confidence: 99%

Cultural System Affects Fruit Quality and Antioxidant Capacity in Strawberries

Wang

Galletta

2002

J. Agric. Food Chem.

265

180

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Cultural system [hill plasticulture (HC) versus matted row (MR)] and genotype interactions affected strawberry fruit quality. In general, fruit soluble solids content, total sugar, fructose, glucose, ascorbic acid, titratable acid, and citric acid contents were increased in the HC system. Fruit from HC also had higher flavonoid contents and antioxidant capacities. Strawberry fruit contains flavonols as well as other phenolic compounds such as anthocyanins and phenolic acids. Pelargonidin-based anthocyanins such as pelargonidin 3-glucoside, pelargonidin 3-rutinoside, and pelargonidin 3-glucoside-succinate were the predominant anthocyanins in strawberry fruit. The content of cyanidin-based anthocyanins, cyanidin 3-glucoside and cyanidin 3-glucoside-succinate, was much lower than that of pelargonidin-based anthocyanins in either system. Strawberry fruit from the HC system had significantly higher amounts of p-coumaroylglucose, dihydroflavonol, quercetin 3-glucoside, quercetin 3-glucuronide, kaempferol 3-glucoside, kaempferol 3-glucuronide, cyanidin 3-glucoside, pelargonidin 3-glucoside, pelargonidin 3-rutinoside, cyanidin 3-glucoside-succinate, and pelargonidin 3-glucoside-succinate. Fruits from plants grown in the MR system generally had the lowest contents of phenolic acids, flavonols, and anthocyanins. Strawberry fruit grown under HC conditions had significantly higher peroxyl radicals (ROO*) absorbance capacity (ORAC).

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Section: Resultsmentioning

confidence: 99%

Cultural System Affects Fruit Quality and Antioxidant Capacity in Strawberries

Wang

Galletta

2002

J. Agric. Food Chem.

265

180

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“…Most of the flavonols including quercetin are also mutagenic in the Ames test and other short-term tests in vitro (Sugimura et al 1977;International Agency for Research on Cancer, 1983). However, other tests in vitro have shown quercetin to be a potent inhibitor of mutagenic activity of food carcinogens, such as heterocyclic aromatic amines (Stavric et al 1990). The same anti-mutagenic activity was found in the livers of mice when quercetin was added to their feed (Stavric, 1994;Stavric et al 1990).…”

Section: Non-nutrient Antioxidants (Javonoids and Other Related Compomentioning

confidence: 95%

“…However, other tests in vitro have shown quercetin to be a potent inhibitor of mutagenic activity of food carcinogens, such as heterocyclic aromatic amines (Stavric et al 1990). The same anti-mutagenic activity was found in the livers of mice when quercetin was added to their feed (Stavric, 1994;Stavric et al 1990). Another test on mice showed the mutagenic effect of heterocylic aromatic amines to be enhanced by quercetin (Rowland, 1993).…”

Section: Non-nutrient Antioxidants (Javonoids and Other Related Compomentioning

confidence: 98%

Functional food science and defence against reactive oxidative species

et al. 1998

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This paper assesses critically the science base that underpins the argument that oxidative damage is a significant causative factor in the development of human diseases and that antioxidants are capable of preventing or ameliorating these disease processes. The assessment has been carried out under a number of headings, and some recommendations for future research are made based on the present day knowledge base.

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“…Kaempferol and quercetin are potent quenchers of ROO · , O and 1 O 2 (Larson, 1988). Quercertin and other polyphenols have been shown to play a protective role in carcinogenesis by reducing the bioavailability of carcinogens (Starvic et al. , 1992).…”

Section: Antioxidant Activity Of Flavonoids and Phenolics In Raspberriesmentioning

confidence: 99%

Preharvest application of methyl jasmonate increases fruit quality and antioxidant capacity in raspberries

Wang¹,

2005

Int J of Food Sci Tech

114

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The effects of preharvest methyl jasmonate (MJ) application on fruit quality, flavonoid content and antioxidant capacity in black raspberry cv. Jewel (Rubus occidentalis L) and red raspberry cv. Autumn Bliss (Rubus idaeus subsp.) were studied under field condition. Raspberries treated with MJ had higher soluble solids content, total sugars, fructose, glucose, sucrose and lower titratable acids (TAs), malic acid and citric acid than untreated fruit. MJ also significantly enhanced the content of flavonoids and the antioxidant capacities in the fruit. The cv. Jewel had higher soluble solids and lower TAs compared with the cv. Autumn Bliss. On the basis of fresh weight of fruit, ÔJewelÕ also had significantly higher anthocyanin, total phenolic content and antioxidant activity than ÔAutumn BlissÕ.

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Effect of Flavonoids on Mutagenicity and Bioavailability of Xenobiotics in Foods

Cited by 19 publications

References 0 publications

Cultural System Affects Fruit Quality and Antioxidant Capacity in Strawberries

Cultural System Affects Fruit Quality and Antioxidant Capacity in Strawberries

Functional food science and defence against reactive oxidative species

Preharvest application of methyl jasmonate increases fruit quality and antioxidant capacity in raspberries

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