Effect of Fish or Soybean Oil-Rich Diets on Bradykinin, Kallikrein, Nitric Oxide, Leptin, Corticosterone and Macrophages in Carrageenan Stimulated Rats

Wohlers, Marta; Xavier, Roberta Araújo Navarro; Oyama, Lila Missae; Ribeiro, Eliane; Nascimento, Cláudia Maria Oller do; Casarini, Dulce Elena; Silveira, Vera Lúcia Flor

doi:10.1007/s10753-006-9002-2

Cited by 9 publications

(13 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the daily energy intake was lower in S and F as compared to C (Table 3). These findings are in accordance with previous data [13,17,42]. The C, L, and CC mice had similar energy intakes.…”

Section: Discussionsupporting

confidence: 93%

“…It has been shown that treatment for 7 weeks with the same soybean oil-enriched diet used in this study increased plasma corticosterone concentrations [42]. The reduced adiponectin gene expression observed in the chronically treated S group may be attributed, at least in part, to an increase in glucocorticoid levels, which, according to Fasshauer et al [11], decrease adiponectin gene expression.…”

Section: Discussionsupporting

confidence: 54%

“…It has been shown that soybean oil-and fish oilenriched diets increase serum leptin levels in rats [42]. Treatment of primary cultured rat adipocytes with EPA Table 4 Adiponectin mRNA quantification in epididymal, retroperitoneal and subcutaneous white adipose tissues of mice fed with the control diet (C) or control diet enriched with 17.5% soybean oil (S), fish oil (F), lard (L), or coconut oil (CC), for 2 days (acute) or 8 weeks (chronic) Results are expressed as mean±SEM as arbitrary units, stipulating 100 as the control value.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue

Bueno

Oyama

Oliveira

et al. 2007

Pflugers Arch - Eur J Physiol

Self Cite

View full text Add to dashboard Cite

Obesity is positively correlated to dietary lipid intake, and the type of lipid may play a causal role in the development of obesity-related pathologies. A major protein secreted by adipose tissue is adiponectin, which has antiatherogenic and antidiabetic properties. The aim of this study was to evaluate the effects of four different high-fat diets (enriched with soybean oil, fish oil, coconut oil, or lard) on adiponectin gene expression and secretion by the white adipose tissue (WAT) of mice fed on a selected diet for either 2 (acute treatment) or 60 days (chronic treatment). Additionally, 3T3-L1 adipocytes were treated for 48 h with six different fatty acids: palmitic, linoleic, eicosapentaenoic (EPA), docosahexaenoic (DHA), lauric, or oleic acid. Serum adiponectin concentration was reduced in the soybean-, coconut-, and lard-enriched diets in both groups. Adiponectin gene expression was lower in retroperitoneal WAT after acute treatment with all diets. The same reduction in levels of adiponectin gene expression was observed in epididymal adipose tissue of animals chronically fed soybean and coconut diets and in 3T3-L1 cells treated with palmitic, linoleic, EPA, and DHA acids. These results indicate that the intake of certain fatty acids may affect serum adiponectin levels in mice and adiponectin gene expression in mouse WAT and 3T3-L1 adipocytes. The effects appear to be time dependent and depot specific. It is postulated that the downregulation of adiponectin expression by dietary enrichment with soybean oil or coconut oil may contribute to the development of insulin resistance and atherosclerosis.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 54%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue

Bueno

Oyama

Oliveira

et al. 2007

Pflugers Arch - Eur J Physiol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Nutrition therapy in critically ill patients may play an important role in assisting recovery and improving outcomes 5 , 6 . The capacity of ω‐3 polyunsaturated fatty acids (PUFAs) to modulate immunologic and inflammatory responses has been recognized for some years 7 – 10 . The biologically active ω‐3 PUFAs are eicosapentaenoic acid (EPA; 20:5ω‐3) and docosahexaenoic acid (DHA; 22:6ω‐3) found in fish oils.…”

Section: Introductionmentioning

confidence: 99%

Pharmaconutrition

Barros

Cassulino

Schalch

et al. 2013

J Parenter Enteral Nutr

View full text Add to dashboard Cite

show abstract

“…8,9) It is therefore conceivable that soybean oil has low toxicity in the lungs because these components inhibit the toxicity of OA.…”

Section: Discussionmentioning

confidence: 99%

Effects of Bolus Injection of Soybean-Based Fat Emulsion and Fatty Acids on Pulmonary Gas Exchange Function

Ishitsuka

Moriuchi

Chen

et al. 2009

Biological & Pharmaceutical Bulletin

View full text Add to dashboard Cite

The unsaturated C-18 fatty acid oleic acid (OA) is known as a potent lung toxicant.1) Intravenous injection of OA to animals produces acute lung injury with hypoxemia and an increase in pulmonary vascular permeability, and has been used as a model of clinical acute lung injury including acute respiratory distress syndrome (ARDS). [1][2][3][4] Soybean-based fat emulsions (SFEs) are clinically used worldwide for nutritional support. SFEs contain a high level of OA (e.g., 22-25% of the fatty acid in Intralipid ® , a formulation of SFE), 5) yet despite this, do not induce lung injury when used properly. The reason for the low pulmonary toxicity of SFEs remains unclear, although it has been postulated that "bolus injection" may induce an acute load of OA to the lungs and subsequent lung injury. However, since SFEs are clinically administered by continuous injection, little has been reported on the effects of "bolus injection" of SFE on pulmonary function.This study was conducted to examine whether a "bolus injection" of SFE induces acute lung injury accompanied by pulmonary gas exchange and/or vascular hyper-permeability as is the case with OA. In addition, we also compared the effect of an injection of SFE with that of OA, soybean oil (a source of SFE), emulsified OA and C-18 fatty acids, namely, stearic, linoleic and linolenic acid, on pulmonary gas exchange and evaluated the possibility of lung injury induced by these lipids. . Other reagents and solvents were of reagent grade. Emulsified OA was prepared by adding 1 ml of OA to 4 ml of cold water using a microsyringe with vibration. This mixture was then sonicated for 5 min. The average particle diameter of the OA emulsion particles was less than 1 mm. The OA emulation was prepared just before use. Deionized distilled water was used throughout. MATERIALS AND METHODS MaterialsAnimal Care and Handling This study was approved by the Animal Care and Use Committee of Kumamoto University. The care and handling of animals were performed in accordance with the National Institutes of Health guidelines for the care and handling of animals. All operations and measurements mentioned below were performed as described previously. 3,4)Measurement of the Partial Oxygen Pressure of Arterial Blood (Pao 2 ) To examine the effect of bolus injection of SFE and other lipids on pulmonary gas exchange (Table 1), we measured Pao 2 . Briefly, guinea pigs were randomly divided into 6 groups and treated with the following: 1) 0.3-4.8 ml/kg SFE; 2) 4.8 ml/kg saline (as a control group); 3) 15-60 ml/kg OA; 4) 65-260 ml/kg soy bean oil; 5) 75-300 ml/kg emulsified OA; or 6) 15 ml/kg C-18 fatty acids (stearic, linoleic or linolenic acid). Reagents were administered through the subclavian vein. Pao 2 was then determined 0, 6, 10, 15, 35, 55, and 75 min after the injection with a To determine whether or not a "bolus injection" of soybean-based fat emulsion (SFE), which contains oleic acid (OA), a potent lung-toxic unsaturated C-18 fatty acid, can induce pulmonary dysfunction, we examined the effect...

show abstract

Effect of Fish or Soybean Oil-Rich Diets on Bradykinin, Kallikrein, Nitric Oxide, Leptin, Corticosterone and Macrophages in Carrageenan Stimulated Rats

Cited by 9 publications

References 58 publications

Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue

Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue

Pharmaconutrition

Effects of Bolus Injection of Soybean-Based Fat Emulsion and Fatty Acids on Pulmonary Gas Exchange Function

Contact Info

Product

Resources

About