Effect of fibromyalgia on bone mineral density in patients with fibromylagia and rheumatoid arthritis

Abstract

In spite of functional disability, FM does not cause a decrease in BMD. The presence of FM in RA patients does not result in a change in BMD.

Concomitant fibromyalgia complicating chronic inflammatory arthritis: a systematic review and meta-analysis

“…The majority of studies were based in single rheumatology departments or clinics [ 11 , 14 , 17 , 18 , 20–22 , 24–29 , 31–33 , 35 , 36 , 37 , 38 , 40 , 41 , 43 , 46–50 , 52 ], some studies used participants from multiple sites or centres [ 30 , 34 , 39 , 42 , 53 ], and some had many centres contributing to a single registry or database [ 13 , 19 , 23 , 45 ]. Study setting also varied by country with five each from the UK [ 14 , 32 , 34 , 36 , 45 ] and the USA [ 18 , 19 , 31 , 39 , 53 ], four each from Brazil [ 21 , 22 , 37 , 18 ] and Italy [ 42 , 43 , 50 , 52 ], three from Egypt [ 26 , 28 , 35 ], France [ 24 , 27 , 46 ] and Turkey [ 11 , 20 , 49 ], two from Denmark [ 23 , 33 ], Israel [ 47 , 51 ], Spain [ 13 , 40 ] and Pakistan [ 17 , 41 ], and one each from Australia […”

“…Amongst the studies that reported disease activity, common reasons for lower scoring were poor description of statistical methods, non-blinding of examiners and important differences between comparison groups. Gender, age and disease duration were well reported in the included studies and 19 papers were assessed as lower quality due to differences between comparison groups for at least one of these factors [ 11 , 13 , 14 , 20 , 22 , 24 , 34 , 36 , 37 , 38 , 40 , 43 , 46–52 ]. Other confounding factors may have been important, but amount of comorbidity and treatment regimen were reported only in a small number of studies.…”

“…Other confounding factors may have been important, but amount of comorbidity and treatment regimen were reported only in a small number of studies. In the reporting studies, the difference in types of anti-inflammatory drugs taken between those with and without FM was generally found to be non-significant [ 13 , 17 , 20 , 21 , 24–26 , 29 , 46 ]. On the other hand, mental health scores for anxiety or depression, or number of participants on regular antidepressants, were significantly worse in the FM group in more than half of the reporting studies [ 14 , 24 , 34 , 35 , 37 , 40 ].…”

“…It was possible to determine an estimate of comorbid FM prevalence from the other 25 RA studies. Many articles additionally assessed the relationship between FM and disease activity [ 14 , 17 , 20–22 , 24–26 , 29 , 32–36 , 37 , 38 , 40 , 41 , 52 ]. The prevalence of FM in patients with RA varied considerably from 4.9% [ 27 ] to 52.4% [ 28 ].…”

Fibromyalgie und seine differenzialdiagnostische Bedeutung bei HWS-Beschwerden

“…Die "weichen" Klassifikationskriterien der Erkrankung und das Fehlen eindeutiger diagnostischer Kriterien führt bei vielen Medizinern zu einer geringen Akzeptanz der Erkrankung, die Diagnose FMS ist daher an sich immer wieder umstritten [7]. [9,10]. Die Vielschichtigkeit des Krankheitsbildes sowie die häufig von den Patienten geäußerten multiplen Beschwerden führen in vielen Fällen zu multiplen Arztbesuchen mit einer daraus resultierenden umfangreichen Diagnostik ( • ▶ Abb.…”