Effect of fibroblast-derived differentiation inducing factor on the differentiation of human monocytoid and myeloid leukemia cell lines

Takeda, Ken; Hosoi, Toshiko; Noda, Miki; Arimura, Hirofumi; Konno, Kunio

doi:10.1016/s0006-291x(88)81044-1

Cited by 19 publications

(10 citation statements)

References 21 publications

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“…For example, IL-6 induces the differentiation of human monocytic leukemia cell lines including THP-1 cells to macrophages capable of producing superoxide, the activity of which is synergistically enhanced in combination with either IL-1, TNF- α , or IFN- γ [210, 211]. Interestingly, we have found that influenza virus infection induces apoptosis and the gene expression of a set of proinflammatory cytokines, such as IL-6, TNF- α , and IFN- β , in cultured human fetal membrane chorion cells [179, 180, 212].…”

Section: Possible Roles Of Proinflammatory and Chemoattractive Cytmentioning

confidence: 99%

Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Virus Infection

Uchide

Ohyama

Bessho³

et al. 2012

Mediators of Inflammation

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Pregnant women are at an increased risk of influenza-associated adverse outcomes, such as premature delivery, based on data from the latest pandemic with a novel influenza A (H1N1) virus in 2009-2010. It has been suggested that the transplacental transmission of influenza viruses is rarely detected in humans. A series of our study has demonstrated that influenza virus infection induced apoptosis in primary cultured human fetal membrane chorion cells, from which a factor with monocyte differentiation-inducing (MDI) activity was secreted. Proinflammatory cytokines, such as interleukin (IL)-6, tumor necrosis factor (TNF)-α, and interferon (IFN)-β, were identified as a member of the MDI factor. Influenza virus infection induced the mRNA expression of not only the proinflammatory cytokines but also chemoattractive cytokines, such as monocyte chemoattractant protein (MCP)-1, regulated on activation, normal T-cell expressed and secreted (RANTES), macrophage inflammatory protein (MIP)-1β, IL-8, growth-regulated oncogene (GRO)-α, GRO-β, epithelial cell-derived neutrophil-activating protein (ENA)-78, and interferon inducible protein (IP)-10 in cultured chorion cells. These cytokines are postulated to associate with human parturition. This paper, therefore, reviews (1) lessons from pandemic H1N1 2009 in pregnancy, (2) production of proinflammatory and chemoattractive cytokines by human fetal membranes and their functions in gestational tissues, and (3) possible roles of cytokines produced by human fetal membranes in the pathology of adverse pregnancy outcomes associated with influenza virus infection.

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Section: Possible Roles Of Proinflammatory and Chemoattractive Cytmentioning

confidence: 99%

Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Virus Infection

Uchide

Ohyama

Bessho³

et al. 2012

Mediators of Inflammation

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“…33,34) Our unpublished data indicate that monocytic THP-1 cells differentiated to macrophages by incubation with a culture supernatant from IV-infected chorion cells undergoing apoptosis, but not by culture supernatant from IVinfected amnion cells in the absence of apoptosis. As inflammatory cytokines such as IL-6, IL-1, TNF-a, IFN-g and GM-CSF are thought to differentiate immature monocytes to mature macrophages, 35) inflammatory cytokines might be induced in IV-infected apoptotic cells to promote phagocytosis of apoptotic host cells by mature macrophage. Accordingly, chorion cells may play a role in defense against IV through the induction of inflammatory cytokine mRNAs and apoptosis, while amnion cells seem to abandon this role.…”

Section: Expression Of Mrnas For Inflammatory Cytokines and Fas In mentioning

confidence: 99%

Differential mRNA Expression of Inflammatory Cytokines in Cultured Human Fetal Membrane Cells Responding to Influenza Virus Infection.

Uchide

Ohyama

Yuan

et al. 2002

Biological & Pharmaceutical Bulletin

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When a virus encounters a susceptible cell, the virus enters and initiates cytocidal, persistent, latent or abortive infection. We recently reported that influenza virus (IV) induces persistent infection accompanied by cell survival and virus production in cultured amnion cells. In addition, cytocidal infection accompanied by apoptotic cell death and virus production occurred in cultured chorion cells. Both cell cultures were prepared from human fetal membranes. 1)IV induces cytocidal infection in a variety of cultures, such as HeLa and Madin-Darby canine kidney (MDCK) cell lines and human peripheral blood monocytes in vitro, all of which die through the mechanism of apoptosis.2-5) Furthermore, IV infection induces gene expression of inflammatory cytokines such as interleukin (IL)-1, IL-6, tumor necrosis factor (TNF)-a and interferon (IFN)-a/b, and C-C and C-X-C chemokines such as monocyte chemoattractant protein (MCP)-1, macrophage inflammatory protein (MIP)-1a, RANTES (regulated on activation, normal T cell expressed and secreted) and IFN-inducible protein (IP)-10, 6,7) and proapoptotic factors such as Fas and Fas ligand,8) which occur in infected host cells undergoing apoptosis. Apoptosis and inducible gene expression of inflammatory mediators therefore seem to be correlated. However, whether IV induces gene expression of inflammatory mediators during persistent infection remains unknown.We therefore extensively examined expression of mRNAs for inflammatory cytokines such as IL-1b, IL-6, TNF-a, IFN-a, IFN-b, IFN-g, macrophage colony-stimulating factor (M-CSF) and granulocyte macrophage colony-stimulating factor (GM-CSF), and Fas during cytocidal and persistent infections by reverse transcriptase-polymerase chain reaction (RT-PCR) analysis. Of note is the fact that IV infection induced the gene expression of a set of inflammatory cytokines during cytocidal infection accompanied by apoptotic cell death, but this induction was not present during persistent infection in the absence of apoptosis. In this paper we report a noticeable difference in gene expression of a set of inflammatory cytokines between cytocidal and persistent infections. MATERIALS AND METHODSMaterials PCR primers for IFN-a, IFN-b, IFN-g, M-CSF and GM-CSF were originally designed according to published cDNA sequences. 9-13) PCR primers for Fas were based on the published DNA sequences for the primers. 14)PCR primers for IL-1b, IL-6, TNF-a and glycerol-3-phosphate dehydrogenase (G3PDH) were purchased from CLON-TECH Labs. Inc. (CA, U.S.A.). DNA sequences for the PCR primers are shown in Table 1. Neutralizing antibodies against Fas (Medical & Biological Labs. Co., Ltd., Nagoya, Japan), IFN-b (Yamasa Shoyu Co., Ltd., Tokyo, Japan), TNF-a and IFN-g (Genzyme Diagnostic, MA, U.S.A.) were purchased from the listed suppliers.Cell Culture and Virus Infection Primary cultured chorion and amnion cells were prepared from human fetal membranes obtained by cesarean section during the month of normal parturition as described.15) HeLa cell line was obtained from...

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“…The NBT-reducing ability was determined by the modified method of Takeda et al (13). Briefly, after treatment with STL or MEL for 2 d, viable cells (2 × 10 5 ) were washed once with ERDF medium and were suspended in 2 mL of ERDF medium containing 5% fetal bovine serum, 0.1% NBT dye in a 12-well plate for 2 h at 37°C in a 5% CO 2 incubator.…”

Section: Methodsmentioning

confidence: 99%

“…Cells were washed again and 2 mL of 0.01% fuchsin solution was added to the cell pellet. The cells containing yeast particles were scored as phagocytosis positive, and at least 200 cells were counted for each experimental point (13).…”

Section: Methodsmentioning

confidence: 99%

Differentiation of human promyelocytic leukemia cell line HL60 by microbial extracellular glycolipids

Isoda

Shinmoto

Kitamoto

et al. 1997

Lipids

110

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Total cellular RNAs from a variety of fresh and culture-derived human hematopoietic neoplastic cell types at various stages of differentiation and human sarcoma, carcinoma, melanoma, and glioblastoma cell lines were enriched for poly(A)-containing sequences, fractionated by gel electrophoresis, and blot hybridized to a cloned DNA probe containing the transforming sequences (v-amv) of avian myeloblastosis virus (AMV), a virus known to cause myeloid leukemias in chickens. Expression of RNA sequences homologous to AMV was detected in all immature my-eloid and lymphoid T cells in addition to the single erythroid cell line examined, but not in mature T cells or in B cells, including lymphoblast cell lines derived from patients with Burkitt lym-phoma. In addition, induction of the cell line HL60, a promyelo-cytic leukemia line, to differentiate with dimethyl sulfoxide or reti-noic acid resulted in a reduction of the level of expression of the human cellular gene c-amy homologous to v-amy. There was no detectable c-amv mRNA in any of the solid tumor cell lines examined. Thus, expression of the human c-amy gene could be correlated with the stage ofdifferentiation ofdifferent hematopoietic cell types determined by morphologic and marker studies. Expression ofc-amy could not be correlated with the extent ofmethylation in HL60 and in HL60 induced to differentiate with dimethyl sulfoxide.

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Effect of fibroblast-derived differentiation inducing factor on the differentiation of human monocytoid and myeloid leukemia cell lines

Cited by 19 publications

References 21 publications

Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Virus Infection

Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Virus Infection

Differential mRNA Expression of Inflammatory Cytokines in Cultured Human Fetal Membrane Cells Responding to Influenza Virus Infection.

Differentiation of human promyelocytic leukemia cell line HL60 by microbial extracellular glycolipids

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