“…They have been shown to have hypocholesterolaemic, anticoagulant, anticarcinogenic, hepatoprotective, hypoglycaemic, immunomodulatory, neuroprotective, anti-inflammatory and anti-oxidant activities (Milgate and Roberts, 1995;Cheeke, 1999). In ruminants, dietary supplementation with saponins has been claimed to improve growth, feed efficiency and health (Mader and Brumm, 1987). These effects have been explained partly by the action of saponins on ruminal microbes, resulting in a decrease in rumen degradability of feed proteins and an increase in microbial protein synthesis in the rumen, which both increase the intestinal flow of amino acids (Makkar and Becker, 1996b).…”