Effect of Facet Joint Injection Versus Systemic Steroids in Low Back Pain

Ribeiro, Luiza Helena; Furtado, Rita Nely Vilar; Konai, Monique Sayuri; Andreo, Ana Beatriz; Rosenfeld, André; Natour, Jamil

doi:10.1097/brs.0b013e3182a76df1

Cited by 41 publications

(47 citation statements)

References 34 publications

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“…Carette et al [27], report some localised pain near injection site. Ribeiro et al [31] report adverse events, noting there were no significant differences between groups. These included; post-procedure pain (n = 9), cutaneous hypochromia (n = 1), increase in blood glucose levels (n = 5), vaginal bleeding (n = 3), dizziness (n = 3) and nausea (n = 3).…”

Section: Conservative Treatmentsmentioning

confidence: 98%

“…We included six trials with a total of N = 434 participants (range 18-109 participants); Lilius [26], Carette [27], Mayer [28], Celik [29], Kawu [30] and Ribeiro [31].…”

Section: Included Studiesmentioning

confidence: 99%

“…Mayer et al used a combination of bupivacaine and a nonspecified depot preparation corticosteroid. Ribeiro [31] used a combination of triamcinolone hexacetonide and lidocaine (Table 1).…”

Section: Injection Procedures and Injectatementioning

confidence: 99%

“…Two trials Lilius [26] and Carette [27] used intra-articular saline as a placebo control, whilst Ribeiro [31] used active injections into para-spinal muscles as a sham control.…”

Section: Sham/placebo Controlsmentioning

confidence: 99%

“…Two of the trials included a sample size calculation for their primary outcomes (Carette [27], Ribeiro [31]). Reason for incomplete follow-up was not reported in one study (Carette [27]), four studies had no loss at follow-up (Lilius [26], Mayer [28], Celik [29], Kawu [30]), one study (Ribeiro [31]) reported four dropouts, three missed followup and one, in the intervention group, died (not related to study).…”

Section: Conservative Treatmentsmentioning

confidence: 99%

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Intra-articular facet joint injections for low back pain: a systematic review

et al. 2016

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PurposeEvidence supporting the use of therapeutic intra-articular facet joint injections for patients with suspected facet joint pain is sparse. A systematic review including a narrative synthesis was carried out to determine if intra-articular facet joint injections with active drug are more effective in reducing back pain and back pain-related disability than a sham procedure or a placebo/inactive injection. Secondly, to determine if intra-articular facet joint injections with active drug or placebo/inactive injection are more effective in reducing back pain and back pain-related disability than conservative treatment. Methods Medline, EMBASE, CINAHL, CENTRAL, Index to Chiropractic Literature and the Cochrane Central Register of Controlled Trials were searched from inception through April 2015. Data were screened and single extraction with independent verification and risk of bias assessment was performed. Results A total of 391 records were screened, and six trials were included. The trials included were small (range 18-109 participants) and overall in terms of pain and disability outcomes most were inconclusive. Only two of the trials report any significant between-group differences in pain (mean difference -1.0, 95 % CI -2.0 to -0.1) and (p = 0.032) or disability (mean difference -3.0, 95 % CI -6.2 to 0.2) and (p = 0.013) outcomes. Conclusions The studies found here were clinically diverse and precluded any meta-analysis. A number of methodological issues were identified. The positive results, whilst interpreted with caution, do suggest that there is a need for further high-quality work in this area.

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Section: Conservative Treatmentsmentioning

confidence: 98%

“…We included six trials with a total of N = 434 participants (range 18-109 participants); Lilius [26], Carette [27], Mayer [28], Celik [29], Kawu [30] and Ribeiro [31].…”

Section: Included Studiesmentioning

confidence: 99%

“…Mayer et al used a combination of bupivacaine and a nonspecified depot preparation corticosteroid. Ribeiro [31] used a combination of triamcinolone hexacetonide and lidocaine (Table 1).…”

Section: Injection Procedures and Injectatementioning

confidence: 99%

“…Two trials Lilius [26] and Carette [27] used intra-articular saline as a placebo control, whilst Ribeiro [31] used active injections into para-spinal muscles as a sham control.…”

Section: Sham/placebo Controlsmentioning

confidence: 99%