Effect of Extragastric Vagotomy on Pancreatic Polypeptide in Dogs

Abstract

The direct vagal innervation of the pancreas in dogs was interrupted by extragastric vagotomy (EGV). The response of pancreatic polypeptide (PP) to a protein meal and to hypoglycemia was compared preoperatively, after EGV and after truncal vagotomy (TV). EGV had no detectable effect on PP secretion under basal or stimulated conditions. After TV, the PP response to a protein meal was reduced and totally abolished in response to insulin hypoglycemia when compared to preoperative results. This indicates that direct innervation of the pancreas is of little importance for the release of PP but that vagal innervation of the stomach is important provided that the vagal fibers to PP cells all pass through these extragastric vagal branches.

From Dismantling the Class Society to Investing in Human Capital: The Rise and Fall of the Selective Student Finance System in Sweden 1939–1964

“…In all areas of Swedish society, writes his biographer, from higher education to military defence, he tried as a government investigator from the 1960s, and as professor of economics from 1971, "to extend the territory of the market and thereby freedom of choice for the individual. " 107 While his argument finally prevailed in the socio-economic student report (SOU 1963:74) it took time before these ideas were generally accepted by society. Ståhl, who is recognised as one of the hidden powers in Sweden, 108 was ahead of his time.…”