Effect of Extracts form Hovenia dulcis Thunb. on Alcohol Concentration in Rats and Men Administered Alcohol.

Okuma, Yutaka; Ishikawa, Hisashi; Ito, Yosio; Hayashi, Yoshioki; Endo, Akira; Watanabe, Tokinori

doi:10.4327/jsnfs.48.167

Cited by 10 publications

(3 citation statements)

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“…No significant differences in efficacy were observed between Korea and China H. dulcis extracts [ 34 ]. Similar results were obtained by two other in vivo experiments conducted by Okuma et al [ 35 ] and Chen et al [ 36 ] Both studies showed a decrease of blood alcohol and acetaldehyde levels in rats and mice [ 35 ]. Specifically, the administration of H. dulcis aqueous extract [ 36 ] significantly increased ADH activity in the liver of mice compared to the control group.…”

Section: Pharmacological Activities Of H Dulcis supporting

confidence: 90%

Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union

et al. 2021

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Hovenia dulcis Thunberg is an herbal plant, belonging to the Rhamnaceae family, widespread in west Asia, USA, Australia and New Zealand, but still almost unknown in Western countries. H. dulcis has been described to possess several pharmacological properties, such as antidiabetic, anticancer, antioxidant, anti-inflammatory and hepatoprotective, especially in the hangover treatment, validating its use as an herbal remedy in the Chinese Traditional Medicine. These biological properties are related to a variety of secondary metabolites synthesized by the different plant parts. Root, bark and leaves are rich of dammarane-type triterpene saponins; dihydrokaempferol, quercetin, 3,3′,5′,5,7-pentahydroflavone and dihydromyricetin are flavonoids isolated from the seeds; fruits contain mainly dihydroflavonols, such as dihydromyricetin (or ampelopsin) and hovenodulinol, and flavonols such as myricetin and gallocatechin; alkaloids were found in root, barks (frangulanin) and seeds (perlolyrin), and organic acids (vanillic and ferulic) in hot water extract from seeds. Finally, peduncles have plenty of polysaccharides which justify the use as a food supplement. The aim of this work is to review the whole scientific production, with special focus on the last decade, in order to update phytochemistry, biological activities, nutritional properties, toxicological aspect and regulatory classification of H. dulcis extracts for its use in the European Union.

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Section: Pharmacological Activities Of H Dulcis supporting

confidence: 90%

Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union

et al. 2021

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“…The total amount of sugar exceeds that from general fruits, since it can reach 42 % (Xiang et al 2012). The fruit, seeds, leaves, roots, and bark of H. dulcis are used for medical purposes in some cultures (Okuma et al 1995;Cho et al 2004).…”

Section: Introductionmentioning

confidence: 97%

Pollen and microsporangium development in Hovenia dulcis (Rhamnaceae): a different type of tapetal cell ultrastructure

et al. 2015

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Despite that there is some literature on pollen morphology of Rhamnaceae, studies addressing general aspects of the microsporogenesis, microgametogenesis, and anther development are rare. The aim of this paper is to describe the ultrastructure of pollen grain ontogeny with special attention to tapetum cytology in Hovenia dulcis. Anthers at different stages of development were processed for transmission and scanning electron microscopy, bright-field microscopy, and fluorescence microscopy. Different histochemical reactions were carried out. The ultrastructural changes observed during the development of the tapetal cells and pollen grains are described. Large vesicles containing carbohydrates occur in the tapetal cell cytoplasm during the early stages of pollen development. Its origin and composition are described and discussed. This is the first report on the ontogeny and ultrastructure of the pollen grain and related sporophytic structures of H. dulcis.

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“…The fruit, seeds, leaves, roots, and bark of H. dulcis are all used in traditional Chinese medicine. It is well known for treating liver diseases [8], and several studies have demonstrated that extracts of H. dulcis or its purified compounds can serve as detoxifying agents for alcohol poisoning [8, 9]. In addition, the wood grain is beautiful, and the wood from these hardwood trees is suitable for furniture.…”

Section: Introductionmentioning

confidence: 99%

High Efficiency Secondary Somatic Embryogenesis in Hovenia dulcis Thunb. through Solid and Liquid Cultures

Yang

2013

The Scientific World Journal

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Embryogenic callus was obtained from mature seed explants on medium supplemented with 2,4-dichlorophenoxyacetic acid. Primary somatic embryos (SEs) can only develop into abnormal plants. Well-developed SEs could be obtained through secondary somatic embryogenesis both in solid and liquid cultures. Temperature strongly affected induction frequency of secondary embryogenesis. Relatively high temperature (30°C) and germinated SEs explants were effective for induction of secondary somatic embryos, and low temperature (20°C) was more suitable for further embryo development, plantlet conversion, and transplant survival. Somatic embryos formed on agar medium had larger cotyledons than those of embryos formed in liquid medium. Supplementing 0.1 mg L−1 6-benzyladenine (BA) was effective for plant conversion; the rate of plant conversion was 43.3% in somatic embryos from solid culture and 36.5% in embryos from liquid culture. In vitro plants were successfully acclimatized in the greenhouse. The protocol established in this study will be helpful for large-scale vegetative propagation of this medicinal tree.

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Effect of Extracts form Hovenia dulcis Thunb. on Alcohol Concentration in Rats and Men Administered Alcohol.

Cited by 10 publications

References 0 publications

Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union

Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union

Pollen and microsporangium development in Hovenia dulcis (Rhamnaceae): a different type of tapetal cell ultrastructure

High Efficiency Secondary Somatic Embryogenesis in Hovenia dulcis Thunb. through Solid and Liquid Cultures

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