Abstract:Marked increases in renal volume commonly occur in states of acute renal injury such as acute tubular necrosis or transplant rejection. This expansion appears to be due to a marked increase in compliance of the kidney. The present study examined whether compliance-mediated expansion of renal volume above normal impairs renal function. In each of 11 dogs, we compared the volume and function of a collagenase-treated kidney (CK) to the contralateral intact kidney (IK), first under control conditions, then when bo… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.