Effect of Exogenous Estrogens on the Male Mammal

The Gross and Microscopic Anatomy of the Uterus Masculinus of Tree Shrews

“…In general, estrogens directly and indirectly: (1) cause the loss of secretory activity and the regression of epithelia of accessory sexual glands derived embryologically from the Wolffian ducts and urogeni tal sinus, (2) stim ulate growth of the fibromuscular tissues in the male urogenital tract, (3) stim ulate hyperplasia and stratified squamous keratination of epithelia of Wolffian duct and urogenital sinus origins, and presum ably mixed Müllerian and urogenital sinus origin (e.g., prostatic utricle), and (4) stim ulate glandular proliferation of epithelia derived embryologically from the Müllerian ducts [42,43,10,3,30].…”

Effect of Lut-Ovocyclin on Some Testicular Enzymes of the Indian Desert Gerbil <I>Meriones hurrianae</I> Jerdon

“…Emmens and Parkes (1947) have reviewed the effects of exogenous estrogens on male mammals. Pallos (1941) and Gardener (1949) observed that estradiol when injected to young rats prevented the testicular descent, produced atrophy and inhibited spermatogenesis.…”

Effect of Oestradiol-3,17ß Dipropionate on Spermatogenesis and Lysosomal Enzymes in the Rat Tests

“…Oestradiol causes regression of the testes and accessory reproductive organs of various mammals [see Emmens and Parkes (1947) and Burrows (1949) for extensive reviews]. Oestrogenic extract of amniotic fluid reduced the gonadotropic activity of the pituitary glands of castrated male and female rats (Meyer et al 1932), and Moore and Price (1930) showed that oestrogen caused a depression of pituitary function in the male, due to a depression of gonadotropin output by the pituitary (Greep and Jones 1950).…”