Effect of exercise in reducing breast and chest-wall pain in patients with breast cancer: a pilot study

Wong, Philip; Muanza, Thierry; Hijal, Tarek; Masse, L; Pillay, Sandy; Chasen, Martin; Lowensteyn, Ilka; Gold, Mitchell; Grover, Samir C.

doi:10.3747/co.19.905

Cited by 17 publications

(14 citation statements)

References 32 publications

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“… 39 Another study found that exercise had several beneficial effects and mitigated chest wall pain in breast cancer patients. 40 Clinical staff could encourage patients with persistent symptoms to exercise to improve symptoms. More study is needed to develop effective strategies to manage persistent symptoms in TB patients after DOTS completion.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of health-related quality of life in patients with tuberculosis who completed treatment in Kiribati

Chu

Reiher

et al. 2017

J Int Med Res

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ObjectiveTo examine the health-related quality of life (HRQoL) and related factors among patients with smear-positive and smear-negative pulmonary tuberculosis (TB) within 2 years after completion of directly observed treatment, short course (DOTS), and to compare their HRQoL with a comparison group of community-dwelling individuals without TB in South Tarawa, Kiribati.MethodsA cross-sectional questionnaire survey was conducted among 206 pulmonary TB patients who had completed DOTS and 214 individuals without TB, from July to September 2012. HRQoL was measured using the Short Form (36) Health Survey (SF-36).ResultsThe patients with TB had a statistically significantly higher physical component summary (PCS) score and mental component summary (MCS) score on the SF-36 than the comparison group after adjustment for background characteristics. However, the differences did not exceed the 3-point threshold for clinically significant differences. Multiple liner regression showed that older age and presence of persistent symptoms after completion of DOTS were related to a lower PCS score in TB patients. Patients who were smear-positive before DOTS treatment had higher MCS scores than those who were smear-negative.ConclusionsOur results suggest the effectiveness of DOTS treatment. Health professionals can enhance HRQoL among posttreatment TB patients by managing their symptoms.

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Section: Discussionmentioning

confidence: 99%

Evaluation of health-related quality of life in patients with tuberculosis who completed treatment in Kiribati

Chu

Reiher

et al. 2017

J Int Med Res

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“…Empirical evidence has shown that rehabilitative exercise programs, which commonly include a combination of resistance training and aerobic exercises, can effectively reduce pain in breast cancer survivors. [10][11][12] Women living with breast cancer who are directed to rehabilitative exercise programs experience an improvement not only in pain levels but also in their ability to engage in activities of daily living, in their psychological health, and in their overall quality of life. [13][14][15] However, despite evidence to support exercise programs to reduce pain related to breast cancer treatment, residual pain and upper-limb discomfort are common complaints in breast cancer survivors, and there is little focus on the duration of effectiveness of such programs for reducing pain after treatment for breast cancer.…”

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confidence: 99%

The long-term effects of posttreatment exercise on pain in young women with breast cancer

Ibrahim¹

2016

JCSO

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The long-term effects of posttreatment exercise on pain in young women with breast cancer B reast cancer is one of the most prevalent cancers in women worldwide, with more than 1 million new cases diagnosed annually. 1 Prognosis for the disease has improved significantly, but 25% to 60% of women living with breast cancer experience some level of pain ranging from mild to severe, the nature of which can evolve from acute to chronic. 2 Pre-, intra-, and post-treatment risk factors have been found to correlate with the development of acute and chronic pain and include young age, type of breast surgery (lumpectomy or total mastectomy), axillary node dissection, radiation therapy, and hormonal therapy. 3-5 Chemotherapy, particularly anthracycline-and taxanebased regimens, has also been shown to induce pain, arthralgia, myalgia, and peripheral neuropathy during treatment. 6 In particular, postradiation pain may result Background Persistent pain after treatment has been identified in breast cancer populations, with prevalence rates ranging from 25%-60%. Age, surgical procedure, axillary node dissection, and radiation therapy have shown correlation with chronic pain development. Objective To conduct a pilot randomized controlled trial targeting young breast cancer patients to determine the effectiveness of a 12-week exercise program on long-term levels of upper-limb pain, as measured by the Brief Pain Inventory-Short Form (BPI-SF), and pain measured by physical examination of specific shoulder movements. Methods Young adults (18-45 years of age) recently diagnosed with breast cancer consenting to participate in this study were randomly allocated to intervention or control groups. The exercise intervention group participated in a 12-week exercise program starting 3-4 weeks after the cessation of radiation therapy, and the control group received standard care consisting of encouragement for an active lifestyle and pamphlets on the benefits of exercise. The location and severity of pain and its interference with daily life were recorded at the following 6 time points: postsurgery and preradiation (T1, baseline), postradiation and preintervention (T2), and 4 points during an 18-month period postradiation (T3-T6 at 3, 6, 12, and 18 months). In addition, clinical physical assessment of range of motion and pain on active shoulder movements were recorded at each time point. Results 59 young breast cancer patients participated in the study (exercise group: n = 29; control group: n = 30). Over the course of the trial, there were no significant differences between study groups in the BPI-SF measures of pain interference and severity scores. Improvements in pain on shoulder movements were noted in the intervention group at 3 and 6 months postintervention (T3 and T4) but were not sustained over time (by T6, 18 months postradiation). Shoulder girdle-chest wall pain improved at 12 and 18 months postradiation in both groups but persisted despite exercise intervention. Recordings of shoulder pain on physical examination of range showed a...

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“…Moreover, the 3-weeks medication scheme reminded patients in the intervention group to return the second questionnaire at the correct date. These return rates are in line with most clinical and HRQoL studies [26,32]. Higher questionnaire return rates, however, would have increased the study's ability to assess the intervention's efficacy.…”

Section: Discussionmentioning

confidence: 49%

Improvements in Health-Related Quality of Life by Comprehensive Cancer Pain Therapy: A Pilot Study with Breast Cancer Outpatients under Palliative Chemotherapy

et al. 2014

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Background: Cancer-related pain is highly prevalent among outpatients with metastatic breast cancer affecting their health-related quality of life (HRQoL). This study evaluates potential effects of comprehensive pharmacologic cancer pain therapy (CPT) on HRQoL. Patients and Methods: 52 outpatients with metastatic breast cancer undergoing palliative chemotherapy participated. 28 patients suffering from moderate to severe cancer pain were offered CPT. 13 patients participated (intervention group), and 15 declined participation (control group). HRQoL was assessed with the Quality of Life Questionnaire (EORTC QLQ-C30) and the breast module QLQ-BR23 at baseline and after 3 weeks. Results: At baseline, 83% of the patients experienced cancer-related pain, of whom 35% were not prescribed any pain medication. HRQoL of all patients was reduced compared to reference scores. After CPT, the intervention group reported significantly alleviated pain and improvement in several HRQoL subscales (Global QoL, Emotional Functioning, Physical Functioning, Future Perspective, Sleeplessness). The control group did not change significantly. Conclusion: This study emphasizes the demand for sufficient pain management in palliative breast cancer outpatients. The combination of CPT as a guidance for the pharmacological aspects of cancer pain management and the EORTC QLQ-C30 as an assessment and surveillance tool appears to be a method that warrants further research.

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Effect of exercise in reducing breast and chest-wall pain in patients with breast cancer: a pilot study

Cited by 17 publications

References 32 publications

Evaluation of health-related quality of life in patients with tuberculosis who completed treatment in Kiribati

Evaluation of health-related quality of life in patients with tuberculosis who completed treatment in Kiribati

The long-term effects of posttreatment exercise on pain in young women with breast cancer

Improvements in Health-Related Quality of Life by Comprehensive Cancer Pain Therapy: A Pilot Study with Breast Cancer Outpatients under Palliative Chemotherapy

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