Effect of Exercise-Based Cardiac Rehabilitation on Left Ventricular Function in Asian Patients with Acute Myocardial Infarction after Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Controlled Trials

Wang, Yanjiao; Chien, Ching‐Wen; Xu, Ying; Tung, Tao‐Hsin

doi:10.3390/healthcare9060774

Cited by 7 publications

(4 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… Participants: All participants were post-PCI patients included in the meta-analysis. Intervention measure: The intervention measures in all studies were ER; five studies ( 34 , 36 , 39 , 43 , 45 ) did not provide details, one study ( 30 ) required plans including Baduanjin, and one study ( 38 ) required integration with traditional Chinese exercises. One study ( 42 ) required the inclusion of high-intensity interval training (HIIT).…”

Section: Resultsmentioning

confidence: 99%

“…LVEF: Twelve meta-analyses ( 30 – 33 , 37 – 40 , 42 – 45 ) assessed LVEF and the GRADE rating of these outcomes were 5/12 ( 31 , 32 , 40 , 43 , 44 ) considered high, 4/12 ( 30 , 33 , 37 , 42 ) considered moderate, and 3/12 considered low ( 30 , 31 , 45 ). The high and moderate evidence outcomes all showed that ER could improve the LVEF in patients after PCI, except one ( 34 ), which was meaningless ( p = 0.23) when comparing HIIT with MICT.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews

Li,

Lu,

Han

et al. 2023

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

ObjectiveWe aimed to evaluate the effects of different exercise rehabilitation (ER) programs on LVEF and the incidence of restenosis in patients after percutaneous coronary intervention (PCI) through a systematic review and an integrated network meta-analysis (NMA) to provide a reference for the clinical formulation of ER programs for PCI patients.MethodsMeta-analyses of the effects of different types of ER programs on LVEF and the incidence of reinfarction in post-PCI patients were retrieved from 11 domestic and foreign databases. The methodological and reporting quality of the included systematic reviews were evaluated using the AMSTAR 2 and PRISMA statements. The GRADE scoring system was used to evaluate the quality of evidence found in the studies included in the meta-analysis, and studies with high and intermediate-quality evidence were qualitatively analyzed. Stata software (version 16.0) was used to conduct an integrated NMA of the original RCTs with moderate and low risk of bias.ResultSixteen meta-analyses were included in this evaluation. The reporting quality of the included meta-analyses was relatively complete, and the methodological quality was low. Seventy RCTs were included in the NMA. The results showed that all types of rehabilitative exercises were safe and effectively increased LVEF and reduced the incidence of coronary restenosis in patients. The comprehensive exercise program was the most likely to improve LVEF, and the comprehensive exercise program, early exercise program, and high-intensity interval exercise were better than aerobic exercise. Comprehensive exercise programs, early exercise programs, and aerobic exercise reduced the incidence of restenosis in patients. However, Chinese Qigong did not reduce the incidence of restenosis in patients, and there was a risk of bias and inconsistency in the quantitative analysis of restenosis incidence.ConclusionComprehensive exercise programs have the greatest therapeutic significance in improving cardiac output and reducing restenosis rates in post-PCI patients. The early exercise program has great potential but requires kinesiologists to work with physicians to structure the program and strengthen out-of-hospital management. Aerobic exercise has the least therapeutic significance, and Chinese Qigong is suitable for promotion based on its better efficacy than aerobic exercise and may be an alternative to aerobic exercise, but more experimental evidence is needed.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, PROSPERO CRD42022374590.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews

Li,

Lu,

Han

et al. 2023

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

show abstract

“…A meta-analysis of RCTs by Yanijao et al shows a statistically significant improvement in the control group regarding left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD), and left ventricular end-systolic volume (LVESV) [ 16]. A study by Agnieszka et al shows that the exercise stress test time and the metabolic equivalent of task (MET), the maximal oxygen consumption (VO2max), and the sixminute walk test (6MWT) score increased significantly (p = 0.0001) [17].…”

Section: Figure 3: Key Components Of Cardiac Rehabilitationmentioning

confidence: 99%

Role of Cardiac Rehabilitation in Improving Outcomes After Myocardial Infarction

Nemani,

Gade,

Panchumarthi

et al. 2023

Cureus

View full text Add to dashboard Cite

Myocardial infarction, an integral part of acute coronary syndrome (ACS), occurs due to atherosclerotic narrowing of the coronary (heart) blood vessels. Acute coronary syndrome, being one of the major cardiovascular diseases (CVDs), has led to a significant amount of mortality and morbidity, the majority of it due to MI. Over a long period following an MI, the physical, psychological, social, emotional, and occupational well-being are greatly impacted. Cardiac rehabilitation (CR) can address the above and help improve long-term well-being and overall quality of life. The benefits of CR include enhanced exercise capacity, risk factor reduction, improved quality of life (QOL), reduced mortality, and hospital readmissions.We used a systematic literature review (SLR) approach in this article to provide a global overview of cuttingedge CR in the post-MI phase. We reviewed 45 articles from journals of good repute published between 2013 and December 1st, 2023, focusing on seven selected papers for in-depth analysis. The analysis was focused on factors such as the positive outcomes of CR and the effects of CR post-MI. There are only a few statistically significant studies in a few domains of CR benefits, namely decreased mortality, cardiac events, depression, depression-associated mortality, hospital readmissions, increased left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD), left ventricular end-systolic volume (LVESV), metabolic equivalent of task (MET), maximal oxygen consumption (VO2max), and the six-minute walk test (6MWT), and as a result, increased physical performance. Further research is needed to enhance the understanding of its mechanisms and statistically prove its effectiveness in all other domains. As CR continues to evolve, referral and participation in CR should be increased as it improves overall health and well-being.

show abstract

“…Finally, completing the exercise training of a CR program is associated with an improvement in cardiorespiratory capacity measured by an increase in the METS achieved in the exercise stress test and has also been associated with an increase in LVEF [ 12 , 13 ]. Whether the improvements in function class and LVEF lead to a change in the low vs. no-low risk stratification (RS) and prognosis is substantially unknown.…”

Section: Introductionmentioning

confidence: 99%

Prognostic Utility of a New Risk Stratification Protocol for Secondary Prevention in Patients Attending Cardiac Rehabilitation

Cabrera-Aguilera

Ivern

Badosa

et al. 2022

JCM

View full text Add to dashboard Cite

Several risk scores have been used to predict risk after an acute coronary syndrome (ACS), but none of these risk scores include functional class. The aim was to assess the predictive value of risk stratification (RS), including functional class, and how cardiac rehabilitation (CR) changed RS. Two hundred and thirty-eight patients with ACS from an ambispective observational registry were stratified as low (L) and no-low (NL) risk and classified according to exercise compliance; low risk and exercise (L-E), low risk and control (no exercise) (L-C), no-low risk and exercise (NL-E), and no-low risk and control (NL-C). The primary endpoint was cardiac rehospitalization. Multivariable analysis was performed to identify variables independently associated with the primary endpoint. The L group included 56.7% of patients. The primary endpoint was higher in the NL group (18.4% vs. 4.4%, p < 0.001). After adjustment for age, sex, diabetes, and exercise in multivariable analysis, HR (95% CI) was 3.83 (1.51–9.68) for cardiac rehospitalization. For RS and exercise, the prognosis varied: the L-E group had a cardiac rehospitalization rate of 2.5% compared to 26.1% in the NL-C group (p < 0.001). Completing exercise training was associated with reclassification to low-risk, associated with a better outcome. This easy-to-calculate risk score offers robust prognostic information. No-exercise groups were independently associated with the worst outcomes. Exercise-based CR program changed RS, improving classification and prognosis.

show abstract

Effect of Exercise-Based Cardiac Rehabilitation on Left Ventricular Function in Asian Patients with Acute Myocardial Infarction after Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Controlled Trials

Cited by 7 publications

References 41 publications

Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews

Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews

Role of Cardiac Rehabilitation in Improving Outcomes After Myocardial Infarction

Prognostic Utility of a New Risk Stratification Protocol for Secondary Prevention in Patients Attending Cardiac Rehabilitation

Contact Info

Product

Resources

About