Effect of Eucaloric High- and Low-Sucrose Diets With Identical Macronutrient Profile on Insulin Resistance and Vascular Risk

Black, Neil; Spence, Michelle; McMahon, R.; Cuskelly, Geraldine; Ennis, C. N.; McCance, David R.; Young, Ian S.; Bell, P. M.; Hunter, Steven

doi:10.2337/db06-0220

Cited by 84 publications

(86 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Excessive intake of sucrose, glucose, and fructose from fruit juices is thought to contribute to the development of diabetes and obesity (5)(6)(7)(8). We propose here that fermenting juices using lactic acid bacteria may solve this problem.…”

Section: Discussionmentioning

confidence: 99%

Decreased sugar concentration in vegetable and fruit juices by growth of functional lactic acid bacteria

Ishii¹,

Matsumoto

Nishida³

et al. 2017

DD&T

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Decreased sugar concentration in vegetable and fruit juices by growth of functional lactic acid bacteria

Ishii¹,

Matsumoto

Nishida³

et al. 2017

DD&T

View full text Add to dashboard Cite

“…Studies also varied with respect to the composition of the basic and intervention diets, which might have influenced the results. For example Black et al (2006) found that a high-sucrose diet (25 E%) resulted in increases in total and LDL cholesterol by 15% and 24%, respectively, compared to the control diet (10 E% sucrose). The authors hypothesise that the higher level of SFA and lower level of PUFA in the high-sucrose diet could have contributed to the cholesterol-raising effect.…”

Section: Serum Lipidsmentioning

confidence: 99%

Scientific Opinion on Dietary Reference Values for carbohydrates and dietary fibre

Products¹

2010

EFS2

410

162

View full text Add to dashboard Cite

This Opinion of the EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA) deals with the establishment of Dietary Reference Values for carbohydrates and dietary fibre. Nutritionally, two broad categories of carbohydrates can be differentiated: "glycaemic carbohydrates", i.e. carbohydrates digested and absorbed in the human small intestine, and "dietary fibre", non-digestible carbohydrates passing to the large intestine. In this Opinion, dietary fibre is defined as non-digestible carbohydrates plus lignin. The absolute dietary requirement for glycaemic carbohydrates is not precisely known but will depend on the amount of fat and protein ingested. The Panel proposes 45 to 60 E% as the reference Intake range for carbohydrates applicable to both adults and children older than one year of age. Although high frequency of intake of sugar-containing foods can increase the risk of dental caries, there are insufficient data to set an upper limit for (added) sugar intake. Based on the available evidence on bowel function, the Panel considers dietary fibre intakes of 25 g/day to be adequate for normal laxation in adults. A fibre intake of 2 g/MJ is considered adequate for normal laxation in children from the age of one year. Although there is some experimental evidence that a reduction of the dietary glycaemic index and glycaemic load may have favourable effects on some metabolic risk factors such as serum lipids, the evidence for a role in weight maintenance and prevention of diet-related diseases is inconclusive. KEY WORDSCarbohydrates, dietary fibre, sugars, added sugars, glycaemic carbohydrates, oligosaccharides, starch, lignin, glycaemic index, glycaemic load, dietary requirements, blood lipids, lipid profile, glucose tolerance, insulin sensitivity, body weight, type 2 diabetes, blood pressure, cardiovascular disease, coronary heart disease, dental caries, gastrointestinal function, colorectal cancer, mineral absorption SUMMARYFollowing a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on Population Reference Intakes for the European population, including carbohydrates and dietary fibre.Nutritionally, two broad categories of carbohydrates can be differentiated: "glycaemic carbohydrates", i.e. carbohydrates digested and absorbed in the human small intestine, and "dietary fibre", non-digestible carbohydrates passing to the large intestine.The main glycaemic carbohydrates are monosaccharides, disaccharides, malto-oligosaccharides, and starch. In this Opinion the term "sugars" is used to cover monosaccharides and disaccharides. The term "added sugars" refers to sucrose, fructose, glucose, starch hydrolysates (glucose syrup, highfructose syrup) and other isolated sugar preparations used as such or added during food preparation and manufacturing. Sugar alcohols (polyols) such as sorbitol, xylitol, mannitol, and lactitol, are usually not included in the term "sugars". However, they are partly metabolised and i...

show abstract

“…The previous long-standing antipathy to sucrose was reinforced during the 1980s by a series of studies suggesting that sucrose aggravated hyperglycaemia and dyslipidaemia. However, later reports cast doubt on these findings, with studies including more subjects and of longer duration; sucrose intakes of up to 200 g/day did not demonstrate such deleterious effects and influenced the decision to relax the recommendations (Abraira & Derler 1988;Bantle, Laine, & Thomas 1986;Black et al 2006;Jellish, Emanuele, & Abraira 1984).…”

Section: Introductionmentioning

confidence: 97%

Does Advice Based on Less Restrictive Sucrose Intake Affect Glycaemic Control in Individuals with Established Type 2 Diabetes?

Cleator¹,

Allan²,

Smith³

et al. 2014

DIAB

View full text Add to dashboard Cite

This 12-month, randomised study of individuals with established type 2 diabetes investigated whether dietary advice emphasising a single message to reduce fat intake, would improve weight loss, glycaemic and lipid control, compared to advice based on the once traditional lowfat, low-sucrose message. Participants (n=37, mean BMI 33.25 (+1.0) kg/m2, age 58.0 (+3.3) years, diabetes duration 6.8 (±0.9) yrs, 51% male), were randomised into 2 dietary groups. The 'moderate-sucrose' group (n=19) were advised to reduce total fat intake only; the 'low-sucrose' group (n=18), to reduce both total fat and total sugar intake. Repeated measures ANOVA determined group effects on anthropometric/biochemical variables and Spearman's rank correlations determined relationships between changes in diet and study variables. Reported energy and fat intake significantly reduced in both groups, with no difference in reported sucrose intake. HbA1c fell in both groups (7.7% -7.1% (low-sucrose) vs 7.6% -7.4% (moderate-sucrose), both p=0.003), with no additional effect of the single dietary message. HOMA-IR fell by 33.4% in the 'low-sucrose' group (p≤0.005), but not in the moderate sucrose group. Advice to relax sucrose intake restrictions in favour of a single low fat message had no additional effect on reported behaviour or glycaemic control.

show abstract

Effect of Eucaloric High- and Low-Sucrose Diets With Identical Macronutrient Profile on Insulin Resistance and Vascular Risk

Cited by 84 publications

References 46 publications

Decreased sugar concentration in vegetable and fruit juices by growth of functional lactic acid bacteria

Decreased sugar concentration in vegetable and fruit juices by growth of functional lactic acid bacteria

Scientific Opinion on Dietary Reference Values for carbohydrates and dietary fibre

Does Advice Based on Less Restrictive Sucrose Intake Affect Glycaemic Control in Individuals with Established Type 2 Diabetes?

Contact Info

Product

Resources

About