Effect of Etomidate vs Propofol for Total Intravenous Anesthesia on Major Postoperative Complications in Older Patients

Abstract

This randomized clinical trial compares the in-hospital morbidity, clinical outcomes, and mortality associated with use of etomidate vs propofol during abdominal surgery in older patients in China.

Effect of systolic blood pressure fluctuations during resuscitation on postoperative complications following meningioma surgery: A retrospective observation study

“…[ 19 ] In a prospective study, Woodfield et al [ 20 ] found that approximately one-third of complications occur between hospital discharge and 30 days postoperatively. Since only in-hospital POCs were considered, as reported in other studies, [ 21 , 22 ] our results might have underestimated the incidence of POCs. In addition to the hemodynamic variability observed in the PACU, our risk factors for POCs after meningioma surgery were largely congruent with those previously reported in the literature: preoperative comorbidities, higher WHO classification, longer operation time, and more intraoperative fluid administration.…”

Etomidate vs Propofol in Older Surgical Patients

“…To the Editor Lu et al reported that, compared with propofol, etomidate anesthesia did not increase overall major in-hospital morbidity after abdominal surgery in older patients, although it induced transient adrenocortical suppression . Although etomidate-induced adrenal insufficiency is temporary, the additional effect of etomidate on adrenal function might exaggerate the adverse outcomes in the setting of baseline adrenal insufficiency .…”

Etomidate vs Propofol in Older Surgical Patients

“…To the Editor I read with interest the article by Lu et al, who found that etomidate anesthesia does not increase postoperative morbidity in older patients compared with propofol. Because their findings are important to current practice, several questions deserve attention.…”