Effect of Ethanol Extract of Tomato (Solanum lycopersicum L.) on Staphylococcus epidermidis in vitro

Pauzan,; Halid, Musparlin; Ratulangi, Wulan Ratia

doi:10.35816/jiskh.v12i1.1022

Cited by 1 publication

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“…18 The study to determine the effectiveness of the ethanolic extract of tomato (Solanum lycopersicum L) against the growth of Staphylococcus epidermidis bacteria in vitro, showed that the diameter of the inhibition zone formed in the positive control was 40.36 mm (potent inhibition), inhibition zones at concentrations of 100, 80, 60, 40, and 20% had solid inhibitory power. 19 Mouth rinses are the most usual and easy way for antiplaque agents to be delivered. The direct damage to oral health, xerostomia seemed independently associated with mouthwashes, may have an effect on these chemical compounds.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial effects of tomato ethanol extract (Solanum lycopersicum L.) against S. mutans and P. gingivalis: a laboratory experiment

Rahmawati,

Kurniawan,

Sanjaya

et al. 2023

Padjadjaran J Dent

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Introduction: Process of dental plaque formation consists of three stages, pellicle formation, initial colonization facultative gram-positive one of microbes is S. mutans, secondary colonization and microbial maturation by Porphyromonas intermedia, P. gingivalis, Fusobacterium nucleatum. Formation of dental biofilm is considered to be main etiology of chronic periodontitis. Bacteria that often involved in chronic periodontitis are P. gingivalis. Tomatoes (Solanum lycopersicum L.) content lycopene compounds, flavonoids, and saponins have been shown to inhibit or kill bacterial growth. The aim is to analyze the antibacterial effect of servo tomato ethanol extract against S. mutans and P. gingivalis. Methods: This research was a laboratory experimental one with a posttest only control group design where observed variable diameter of the inhibition zone was produced from ethanolic extract of tomato (Solanum lycopersicum L.) in various concentrations of 3.125, 6.25, 12.5, 25, 50 and 100% chlorhexidine 0.2% as a positive control, negative control of distilled water against S. mutans and P. gingivalis on blood agar media. The method used in this study was the well-diffusion test. Results: The highest inhibitory zone at 100% concentration with a diameter of 32.10 mm was very strong; lowest inhibition at 3.123% was 3.95 mm, weak classification and against P. gingivalis at 3.125%, it was 3.72 mm, weak classification, meanwhile at 100% concentration, it was 9.67 mm, medium classification. The results of the One Way ANOVA statistical test showed a p<0.05 which had a significant effect in inhibiting the growth of S. mutans and P. gingivalis. Conclusions: There was an antibacterial effect of the ethanolic extract of tomato against S.mutans produced a larger diameter and stronger inhibition zone meanwhile against P.gingivalis produce medium inhibition zone. The content of tomatoes such as lycopene compounds, flavonoids, and saponins have been shown to inhibit or kill bacterial growth.Keyword : tomato ethanol extract (Solanum lycopersicum L.), S. mutans, P. gingivalis, antibacterial

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Section: Introductionmentioning

confidence: 99%